Nutritional Strategies for Battling Obesity-Linked Liver Disease: the Role of Medical Nutritional Therapy in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Management

被引：17

作者：

Simancas-Racines, Daniel ^{[1
]}

Annunziata, Giuseppe ^{[2
]}

Verde, Ludovica ^{[3
]}

Fasci-Spurio, Federica ^{[4
]}

Reytor-Gonzalez, Claudia ^{[1
]}

Muscogiuri, Giovanna ^{[5
,6
,7
]}

Frias-Toral, Evelyn ^{[8
]}

Barrea, Luigi ^{[9
]}

机构：

[1] Univ UTE, Fac Ciencias Salud Eugenio Espejo, Ctr Invest Salud Publ & Epidemiol Clin CISPEC, Quito 170527, Ecuador

[2] Univ Telemat Pegaso, Fac Sci Umane Formaz & Sport, Via Porzio,Ctr Direz,Isola F2, I-80143 Naples, Italy

[3] Univ Naples Federico II, Dept Publ Hlth, Naples, Italy

[4] Osped Angelo, Gastroenterol Unit, Venice, Italy

[5] Univ Napoli Federico II, Dipartimento Med Clin & Chirurg, Unita Endocrinol Diabetol & Androl, Via Sergio Pansini 5, I-80131 Naples, Italy

[6] Univ Napoli Federico II, Ctr Italiano Cura & Benessere Paziente Con Obes CI, Dipartimento Med Clin & Chirurg, Unita Endocrinol Diabetol & Androl, Via Sergio Pansini 5, I-80131 Naples, Italy

[7] Univ Federico II, Cattedra Unesco Educ Salute & Allo Sviluppo Sosten, I-80131 Naples, Italy

[8] Univ Espiritu Santo, Escuela Med, Samborondon 0901952, Ecuador

[9] Univ Telemat Pegaso, Dipartimento Psicol & Sci Salute, Ctr Direz Isola F2,Via Porzio, I-80143 Naples, Italy

来源：

CURRENT OBESITY REPORTS | 2025年 / 14卷 / 01期

关键词：

Obesity; Medical Nutritional Therapy (MNT); Metabolic-Associated Steatotic Liver Disease (MASLD); Mediterranean diet; Nutraceutical supplementation; Liver fibrosis; NONALCOHOLIC FATTY LIVER; HEALTHY EATING INDEX; WEIGHT-LOSS; DIETARY FIBER; LIFE-STYLE; INSULIN-RESISTANCE; PRACTICE GUIDANCE; PATHOPHYSIOLOGY; PREVALENCE; FIBROSIS;

D O I：

10.1007/s13679-024-00597-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of ReviewThis narrative review explores the role of Medical Nutritional Therapy (MNT) in managing Metabolic-Associated Steatotic Liver Disease (MASLD), previously known as nonalcoholic fatty liver disease. It aims to examine the effectiveness of specific nutritional strategies in preventing and treating this obesity-linked liver disease.Recent FindingsEmerging evidence underscores the benefits of the Mediterranean diet, low-carbohydrate diets, and intermittent fasting in reducing liver fat, improving insulin sensitivity, and mitigating inflammation. Supplementing with vitamin E, omega-3 fatty acids, and silymarin can potentially reduce liver fibrosis and promote liver health.SummaryMNT is a key intervention for MASLD management, emphasizing dietary patterns, caloric restriction, and nutraceutical supplementation. Integrating these strategies with lifestyle modifications, including regular physical activity, offers a comprehensive approach to improving metabolic and liver outcomes in patients with MASLD. Further research is needed to refine and personalize these therapeutic interventions.

引用

页数：16

共 127 条

[1] The Many Faces of Metabolic Dysfunction-Associated Fatty Liver Disease Treatment: From the Mediterranean Diet to Fecal Microbiota Transplantation [J].