The discriminatory ability of wrist and neck circumference in predicting insulin resistance in overweight and obese children

被引：0

作者：

Hamid Asayesh ^{[1
]}

Ali Dehghan ^{[2
]}

Sahar Sobhani ^{[3
]}

Fereshteh Bayegi ^{[4
]}

Sayeh Rostami ^{[2
]}

Fatemeh Aghamahdi ^{[5
]}

Mostafa Qorbani ^{[6
]}

机构：

[1] Department of Nursing, Qom University of Medical Sciences, Qom

[2] Student Research Committee, Alborz University of Medical Sciences, Karaj

[3] Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj

[4] Research Unit of General Practice, Department of Public Health, University of Southern Denmark, Odense

[5] Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj

[6] Department of Pediatric Endocrinology, School of Medicine, Alborz University of Medical Sciences, Karaj

来源：

Journal of Diabetes & Metabolic Disorders | / 24卷 / 1期

关键词：

Children; Insulin resistance; Neck circumference; Obesity; Overweight; Wrist circumference;

D O I：

10.1007/s40200-025-01603-x

中图分类号：

学科分类号：

摘要：

Objectives: The aim of this study was to investigate the association of wrist circumference (WrC) and neck circumferences (NC) with Insulin Resistance (IR) in obese and overweight children and adolescents. Methods: This cross-sectional study included 227 overweight and obese children. Anthropometric indices such as NC and WrC were measured. Laboratory parameters such as fasting blood glucose (FBS) and insulin were measured after 12 h of overnight fasting. IR was determined by Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) using formula and HOMA-IR ≥ 2.6 defined as IR. The predictive power of NC and WrC for IR was assessed using receiver operating characteristic (ROC) analyses and the area under ROC curve (AUC) > 0.65 were considered as highly accurate tests. Results: Among the 227 included samples, 52.4% were girls, and 67.4% were classified as obese. IR was detected in 48.5% of the participants without a significant association with gender (48.8% in girls and 48.1% in boys) and weight status (43.2% in overweight and 51% in obese). The AUCs of WrC and NC in detecting IR were 0.78 (95% CI: 0.72–0.84) and 0.72 (95% CI: 0.65–0.78) in overweight and obese children respectively. The Chi-square test shows that the AUC of WrC in predicting IR was statistically higher than NC (Chi-square: 4.47, P: 0.03). Conclusions: Our findings showed that WrC and NC are two useful indices for predicting IR in overweight and obese children and adolescents. Therefore they could be used as a clinical indicators of IR in children and adolescents. © The Author(s), under exclusive licence to Tehran University of Medical Sciences 2025.

引用

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