Gut microbiota as a new target for anticancer therapy: from mechanism to means of regulation

被引:5
作者
Sun, Jiaao [1 ]
Song, Shiyan [1 ]
Liu, Jiahua [1 ]
Chen, Feng [1 ]
Li, Xiaorui [2 ]
Wu, Guangzhen [1 ]
机构
[1] Dalian Med Univ, Affiliated Hosp 1, Dept Urol, Dalian, Peoples R China
[2] China Med Univ, Dalian Univ Technol, Liaoning Canc Hosp & Inst, Canc Hosp,Dept Oncol, Shenyang, Peoples R China
关键词
COLORECTAL-CANCER; ANTI-PD-1; EFFICACY; ESCHERICHIA-COLI; DIETARY FIBER; BILE-ACIDS; BACTERIA; TRANSPLANTATION; PROBIOTICS; RESISTANCE; RADIOTHERAPY;
D O I
10.1038/s41522-025-00678-x
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
In order to decipher the relationship between gut microbiota imbalance and cancer, this paper reviewed the role of intestinal microbiota in anticancer therapy and related mechanisms, discussed the current research status of gut microbiota as a biomarker of cancer, and finally summarized the reasonable means of regulating gut microbiota to assist cancer therapy. Overall, our study reveals that the gut microbiota can serve as a potential target for improving cancer management.
引用
收藏
页数:20
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