The Influence of Exogenous Particles on the Behavior of Non-Newtonian Mucus Fluid

被引:0
作者
Penconek, Agata [1 ]
Michalczuk, Urszula [1 ]
Magnuska, Malgorzata [1 ]
Moskal, Arkadiusz [1 ]
机构
[1] Warsaw Univ Technol, Fac Chem & Proc Engn, PL-00645 Warsaw, Poland
关键词
non-Newtonian fluid; exogenous particles; Kelvin-Helmholtz instabilities; droplets; DIESEL EXHAUST PARTICLES; INSOLUBLE IRIDIUM PARTICLES; INHALED NANOPARTICLES; SIZE; LUNG; TRANSLOCATION; DEPOSITION; CLEARANCE; TRANSPORT; IMPACT;
D O I
10.3390/pr12122765
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
Every day, approximately 7 m3 of air flows through the lungs of an adult, which comes into contact with 80 m2 of the lung surface. This air contains both natural and anthropogenic particles, which can deposit on the surface of the mucus lining the respiratory tract. The presence of particles in the mucus leads to changes in its rheology and, consequently, in its functions. Therefore, this research aimed to determine how a non-Newtonian fluid suspension will behave during flow, illustrating the movement of mucus during coughing. The model mucus was an aqueous solution of carboxymethylcellulose (CMC). The tested particles suspended in a non-Newtonian fluid were Arizona Fine Dust, diesel exhaust particles, polyethylene microparticles, and pine pollen. It was noticed that as the fluid viscosity increases, the number of Kelvin-Helmholtz instabilities increases. The fluid's expansion angle at the output of the measuring cell decreased, and the values of parameters characterizing the aerosol generated at the outlet decrease for selected particles present in the fluid. The research shows that the deposition of particles from polluted air in the respiratory tract, although they do not enter the bloodstream, may affect the human body. Deposited particles can change the behavior of mucus, which may translate into its functions.
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页数:16
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