The effect of non-pharmacological interventions on cognitive function in cancer: an overview of systematic reviews

被引:2
|
作者
Haywood, Darren [1 ,2 ,3 ,4 ]
Henneghan, Ashley M. [5 ,6 ]
Chan, Alexandre [7 ]
Chan, Raymond J. [8 ]
Dhillon, Haryana M. [9 ]
Lustberg, Maryam B. [10 ]
Vardy, Janette L. [11 ]
O'Connor, Moira [4 ]
Elvidge, Norah [12 ]
Dauer, Evan [1 ,2 ]
Franco-Rocha, Oscar Y. [5 ]
Vasan, Shradha [2 ]
Murray, James [1 ]
Crichton, Megan [12 ]
Wilding, Helen [14 ]
Rossell, Susan L. [2 ,13 ]
Hart, Nicolas H. [1 ,8 ,15 ,16 ,17 ]
机构
[1] Univ Technol Sydney UTS, INSIGHT Res Inst, Fac Hlth, Human Performance Res Ctr, Driver Ave,Moore Pk, Sydney, NSW 2021, Australia
[2] St Vincents Hosp Melbourne, Dept Mental Hlth, Fitzroy, Vic, Australia
[3] Univ Melbourne, Melbourne Med Sch, Dept Psychiat, Dent & Hlth Sci, Parkville, Vic, Australia
[4] Curtin Univ, Fac Hlth Sci, Sch Populat Hlth, Bentley, WA, Australia
[5] Univ Texas Austin, Sch Nursing, Austin, TX USA
[6] Univ Texas Austin, Dell Med Sch, Dept Oncol, Austin, TX USA
[7] Univ Calif Irvine, Sch Pharm & Pharmaceut Sci, Irvine, CA USA
[8] Flinders Univ S Australia, Caring Futures Inst, Coll Nursing & Hlth Sci, Adelaide, SA, Australia
[9] Univ Sydney, Fac Sci, Sch Psychol, Psychooncol Cooperat Res Grp, Sydney, Australia
[10] Yale Univ, Sch Med, New Haven, CT USA
[11] Univ Sydney, Fac Med & Hlth, Sydney, Australia
[12] Queensland Univ Technol, Fac Hlth, Canc & Palliat Care Outcomes Ctr, Sch Nursing, Brisbane, Australia
[13] Swinburne Univ Technol, Ctr Mental Hlth & Brain Sci, Hawthorn, Vic, Australia
[14] St Vincents Hosp Melbourne, Lib Serv, Fitzroy, Vic, Australia
[15] Edith Cowan Univ, Exercise Med Res Inst, Sch Med & Hlth Sci, Perth, WA, Australia
[16] Queensland Univ Technol QUT, Fac Hlth, Canc & Palliat Care Outcomes Ctr, Brisbane, Qld, Australia
[17] Univ Notre Dame Australia, Inst Hlth Res, Perth, WA, Australia
基金
英国医学研究理事会; 美国国家卫生研究院;
关键词
Cancer; Cognition; Cancer-related cognitive impairment; Non-pharmacological; Intervention; Exercise; Cognitive rehabilitation; QUALITY-OF-LIFE; BREAST-CANCER; NERVOUS-SYSTEM; NECK-CANCER; IMPAIRMENT; SURVIVORS; EXERCISE; CHEMOTHERAPY; METAANALYSIS; DYSFUNCTION;
D O I
10.1007/s00520-025-09212-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PurposeA significant number of cancer survivors experience cancer-related cognitive impairment (CRCI), which can impact their ability to think, reason, make decisions, and perform daily actions. In recent years, non-pharmacological interventions for CRCI have gained significant attention. These interventions include exercise, cognitive behavioural therapy, cognitive training/remediation, dietary, mind-body, and multi-modal/complex interventions. This umbrella review provides a critical overview to inform guidelines and current practice, identify the most promising interventions, and uncover gaps in the research literature.MethodsThis umbrella review of systematic reviews was pre-registered on Open Science Framework and PROSPERO. Six databases were searched. Systematic reviews (SR) assessing any non-pharmacological interventions to improve cognition in cancer (any type) were included. The overview followed gold-standard guidelines and recommendations. The results were narratively synthesised, and descriptive statistics and effect size ranges were calculated.ResultsSixty-four (n = 64) SRs were included. Results were synthesised into four non-pharmacological domains. Cognitive training/rehabilitation had the strongest evidence for efficacy. Physical activity/exercise showed promising efficacy; however, the variability of findings was considerable. Mind-body and psychological/behavioural therapy interventions were limited, but there was evidence for short-term effectiveness. Multi-modal/complex interventions showed potential for improving cognition in cancer but were poorly defined.ConclusionsOverall, non-pharmacological interventions demonstrated efficacy for improving cognition in cancer. There were limited intervention characteristics within domains which were consistently related to efficacy. Three key recommendations are provided for future research: (1) adopt harmonisation and reporting guidelines; (2) develop definitional guidelines of cognitive domains for CRCI research; and (3) assess intervention and participant characteristics associated with positive versus null/negative findings.
引用
收藏
页数:45
相关论文
共 50 条
  • [41] Effect of non-pharmacological interventions in people with cognitive frailty: a systematic review and network meta-analysis
    Peng, Junjie
    Chang, Renjie
    Wei, Xinghong
    Yin, Zhimin
    Liu, Qin
    BMC PUBLIC HEALTH, 2024, 24 (01)
  • [42] Effectiveness of exercise interventions in the management of cancer-related fatigue: a systematic review of systematic reviews
    Zhang, Ya-Bin
    Zhong, Xue-Mei
    Han, Ni
    Tang, Huang
    Wang, Shui-Yu
    Lin, Wen-Xuan
    SUPPORTIVE CARE IN CANCER, 2023, 31 (03)
  • [43] Community-based non-pharmacological interventions for pregnant women with gestational diabetes mellitus: a systematic review
    Igwesi-Chidobe, Chinonso Nwamaka
    Okechi, Peace Chioma
    Emmanuel, Grace Nneoma
    Ozumba, Benjamin C.
    BMC WOMENS HEALTH, 2022, 22 (01)
  • [44] Expanding horizons in pulmonary hypertension management: A systematic review and meta-analysis of non-pharmacological interventions
    Albulushi, Arif
    De Silva, Thihan D.
    Kashoub, Masoud
    Tawfek, Ahmed
    Shams, Ahmed
    Al-Riyami, Adil
    Al-Kindi, Fahad
    Bader, Feras
    CURRENT PROBLEMS IN CARDIOLOGY, 2024, 49 (12)
  • [45] Impact of non-pharmacological interventions on quality of life, anxiety, and depression scores in patients with colorectal cancer: a systematic review and meta-analysis of randomized controlled trials
    Meng, Xinyu
    Wang, Xiaodong
    Dong, Zaiquan
    SUPPORTIVE CARE IN CANCER, 2021, 29 (10) : 5635 - 5652
  • [46] Outcomes Related to Activity Performance and Participation of Non-Pharmacological Cancer-Related Fatigue Interventions
    Schroder, Jodie
    Mackenzie, Lynette
    OTJR-OCCUPATION PARTICIPATION AND HEALTH, 2022, 42 (01) : 50 - 64
  • [47] Effectiveness of nursing interventions among patients with cancer: An overview of systematic reviews
    Tuominen, Leena
    Stolt, Minna
    Meretoja, Riitta
    Leino-Kilpi, Helena
    JOURNAL OF CLINICAL NURSING, 2019, 28 (13-14) : 2401 - 2419
  • [48] EFFECTIVENESS OF REHABILITATION INTERVENTIONS IN PATIENTS WITH COLORECTAL CANCER: AN OVERVIEW OF SYSTEMATIC REVIEWS
    Yang, Mengzhe
    Amatya, Bhasker
    Malik, Sana
    Song, Krystal
    Marcella, Stefanie
    Voutier, Catherine
    Khan, Fary
    JOURNAL OF REHABILITATION MEDICINE, 2025, 57
  • [49] Effects of non-pharmacological interventions on gut microbiota and intestinal permeability in older adults: A systematic review Non-pharmacological interventions on gut microbiota/barrier
    Hisham, Hazwanie Iliana Hairul
    Lim, Siong Meng
    Neoh, Chin Fen
    Majeed, Abu Bakar Abdul
    Shahar, Suzana
    Ramasamy, Kalavathy
    ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2025, 128
  • [50] Effects of exercise interventions on cancer-related fatigue in breast cancer patients: an overview of systematic reviews
    Zhou, Hong-Juan
    Wang, Tao
    Xu, Yong-Zhi
    Chen, Yan-Nan
    Deng, Li-Jing
    Wang, Chang
    Chen, Jin-Xiu
    Tan, Jing-Yu
    SUPPORTIVE CARE IN CANCER, 2022, 30 (12) : 10421 - 10440