Health related quality of life and its influencing factors in Chinese patients with ocular tumors

被引：1

作者：

Zhang, Yongmei ^{[1
,2
,3
,4
]}

Peng, Wen ^{[1
,2
,3
]}

Zhao, Xiaojun ^{[1
,2
,3
]}

Zhu, Yiwen ^{[1
,2
,3
]}

Chen, Huifang ^{[1
,2
,3
]}

机构：

[1] Shanghai Jiao Tong Univ, Peoples Hosp 9, Sch Med, Dept Nursing, Shanghai 200011, Peoples R China

[2] Shanghai Jiao Tong Univ, Peoples Hosp 9, Sch Med, Dept Ophthalmol, Shanghai 200011, Peoples R China

[3] Shanghai Key Lab Orbital Dis & Ocular Oncol, Shanghai 200011, Peoples R China

[4] Shanghai Jiao Tong Univ, Sch Nursing, Shanghai 200025, Peoples R China

来源：

SCIENTIFIC REPORTS | 2025年 / 15卷 / 01期

关键词：

Ocular tumor; Health-related quality of life; Coping style; Fear of progression; Medical coping modes Questionnaire; Euro-Qol-5; dimensions; Visual impairment;

D O I：

10.1038/s41598-025-88747-1

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Background: Ocular tumors are a class of important ophthalmologic diseases that threaten patient visual acuity and health-related quality of life (HRQoL). However, little is known about the factors affecting HRQoL among individuals with ocular tumors in mainland China. Methods: Convenience sampling was employed to select 144 patients with ocular tumors being treated in a grade A tertiary hospital in Shanghai from August 2022 to May 2023 as study participants. A self-made general data questionnaire, the Medical Coping Modes Questionnaire (MCMQ), Fear of Progression Questionnaire Short Form (FoP-Q-SF), and Euro-Qol-5 Dimensions (EQ-5D-3 L) were used to conduct a cross-sectional survey. Multiple linear regression was performed to analyze the factors affecting QoL. Results: The mean EQ-5D-3 L visual analog score was 81.60 +/- 17.66 and the most common problems reported by patients with ocular tumors were pain, discomfort, anxiety, and depression. The total MCMQ score was 39.88 +/- 7.04, and the total FoP-Q-SF score was 25.24 +/- 9.27. The health effects index was negatively correlated with avoidance (r = - 0.226, p < 0.05) and resignation dimensions (r = - 0.460, p < 0.05) and negatively correlated with total FoP-Q-SF score (r = - 0.491, p < 0.001). Multiple linear regression analysis showed that having a resignation coping style, high FOP, low visual acuity in the non-dominant eye, and diagnosis of malignant tumor is significantly associated with low HRQoL ( p < 0.05). Conclusions: The HRQoL of patients with ocular tumors tends to be low. HRQoL in these patients is associated with increased MCMQ resignation domain score, FoP-Q-SF physical health domain score, definitive diagnosis of malignancy, and decreases in non-dominant eye visual acuity. We recommend that clinical staff focus on improving non-dominant eye visual acuity in patients with ocular tumors and improve their disease coping styles to decrease FOP, thereby increasing their QoL.

引用

页数：9

共 42 条

[11] DEGREE OF LIFE-THREAT AND DIFFERENTIAL USE OF COPING MODES [J].