Synthesis of Polysubstituted Furans from α-Substituted 2-Enals

被引:0
|
作者
Fedoseeva, V. G. [1 ]
Verochkina, E. A. [1 ]
Larina, L. I. [1 ]
Vchislo, N. V. [1 ]
机构
[1] Russian Acad Sci, Siberian Branch, Favorskii Irkutsk Inst Chem, Irkutsk 664033, Russia
关键词
alpha; beta-unsaturated aldehydes; polysubstituted furans; ketenimines; multicomponent reactions;
D O I
10.1134/S1070428024110095
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The three-component reaction of cyclohexyl isocyanide, dimethyl acetylenedicarboxylate, and (Z)-3-phenyl-2-(alkylsulfanyl)- or (Z)-3-furyl-2-methoxyprop-2-enals gives polysubstituted furans in good yields.
引用
收藏
页码:2157 / 2161
页数:5
相关论文
共 50 条
  • [21] Regioselective synthesis of 2-carbonyl furans in a one pot three component reaction
    Kale, Ashok
    Medishetti, Nagaraju
    Nanubolu, Jagadeesh Babu
    Atmakur, Krishnaiah
    TETRAHEDRON LETTERS, 2018, 59 (47) : 4168 - 4171
  • [22] A new chiral C1-symmetric NHC-catalyzed addition to α-aryl substituted α,β-disubstituted enals: enantioselective synthesis of fully functionalized dihydropyranones
    Lu, Hong
    Liu, Jin-Yu
    Li, Chen-Guang
    Lin, Jun-Bing
    Liang, Yong-Min
    Xu, Peng-Fei
    CHEMICAL COMMUNICATIONS, 2015, 51 (21) : 4473 - 4476
  • [23] Titanium-Mediated Domino Cross-Coupling/Cyclodehydration and Aldol-Addition/Cyclocondensation: Concise and Regioselective Synthesis of Polysubstituted and Fused Furans
    Ren, Lu
    Luo, Juan
    Tan, Linbo
    Tang, Qiang
    JOURNAL OF ORGANIC CHEMISTRY, 2022, 87 (05) : 3167 - 3176
  • [24] Extended Version of the Corey-Chaykovsky Reaction: Synthesis of 2,4-Substituted Furans by the Treatment of β-Dialkylamino Chalcones with Dimethylsulfonium Methylide
    Shcherbakov, Roman O.
    Myasnikov, Danil A.
    Trushkov, Igor V.
    Uchuskin, Maxim G.
    JOURNAL OF ORGANIC CHEMISTRY, 2023, 88 (13) : 8227 - 8235
  • [25] Oxidative Cross-Coupling of Allenyl Ketones and Organoboronic Acids: Expeditious Synthesis of Highly Substituted Furans
    Xia, Ying
    Xia, Yamu
    Ge, Rui
    Liu, Zhen
    Xiao, Qing
    Zhang, Yan
    Wang, Jianbo
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (15) : 3917 - 3921
  • [26] A calcium catalysed regioselective (5-exo dig) tandem process for the synthesis of fully substituted furans
    Yaragorla, Srinivasarao
    Dada, Ravikrishna
    Pareek, Abhishek
    Singh, Garima
    RSC ADVANCES, 2016, 6 (34) : 28865 - 28870
  • [27] DABCO-Catalyzed Synthesis of Trifluoromethylated Furans from Propargyl Alcohols and Methyl 2-Perfluoroalkynoate
    Chong, Qinglei
    Xin, Xiaoyi
    Wang, Chunxiang
    Wu, Fan
    Wang, Haolong
    Shi, Ji-cheng
    Wan, Boshun
    JOURNAL OF ORGANIC CHEMISTRY, 2014, 79 (05) : 2105 - 2110
  • [28] Modular Pyridine Synthesis from Oximes and Enals through Synergistic Copper/Iminium Catalysis
    Wei, Ye
    Yoshikai, Naohiko
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (10) : 3756 - 3759
  • [29] Diastereoselective multicomponent Amine-Aldehyde-Dienophile (AAD) process for the synthesis of polysubstituted cyclohex-2-enylamines
    Selva, Veronica
    Chabour, Ihssene
    Najera, Carmen
    Sansano, Jose M.
    TETRAHEDRON, 2019, 75 (10) : 1315 - 1321
  • [30] A Novel Method for Synthesis of 2,3,4-Trisubstituted Furans
    Lu Bin XU
    ChineseChemicalLetters, 2006, (11) : 1421 - 1422