Chronic airway inflammatory diseases and e-cigarette use: a review of health risks and mechanisms

被引:0
作者
Yang, Xing [1 ]
Che, Wenqi [1 ]
Zhang, Lu [1 ]
Zhang, Huanping [1 ,2 ,3 ]
Chen, Xiaoxue [2 ,3 ]
机构
[1] Shanxi Med Univ, Shanxi Bethune Hosp, Tongji Shanxi Hosp, Shanxi Acad Med Sci,Hosp 3, Taiyuan 030032, Peoples R China
[2] Shanxi Med Univ, Shanxi Bethune Hosp, Tongji Shanxi Hosp, Shanxi Acad Med Sci,Hosp 3, Taiyuan 030032, Peoples R China
[3] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Peoples R China
关键词
E-cigarettes; Airway inflammation; Chronic obstructive pulmonary disease; Asthma; Inflammatory mediators; SMOKING; TOBACCO; ADULTS; COPD;
D O I
10.1186/s40001-025-02492-9
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Chronic airway inflammatory diseases, which primarily include chronic obstructive pulmonary disease (COPD), asthma, allergic rhinitis, and chronic sinusitis, continue to have a high global prevalence, highlighting their significant public health impact. Concurrently, the use of e-cigarettes (tobacco e-cigarettes) has been rising worldwide, with many users perceiving them as a safer alternative to traditional cigarettes. However, accumulating evidence from international studies suggests that e-cigarettes pose substantial health risks. This review aims to explore recent research on the relationship between e-cigarette use and chronic airway inflammatory diseases. The findings indicate that e-cigarette usage increases the risk of developing these conditions. Specifically, studies have shown that e-cigarettes exacerbate airway inflammatory responses, elevate levels of type 2 inflammatory cytokines such as IL-4, IL-5, and IL-13, increase cellular oxidative stress, and impair lung function. These mechanisms may collectively contribute to an increased risk of chronic airway inflammatory diseases potentially associated with e-cigarette use.
引用
收藏
页数:12
相关论文
共 105 条
  • [41] Impact of vaping on respiratory health
    Jonas, Andrea
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2022, 378
  • [42] Kalininskiy Aleks, 2021, Pediatr Med, V4, DOI 10.21037/pm-20-97
  • [43] Effects of Combustible Cigarettes and Electronic Nicotine Delivery Systems on the Development and Progression of Chronic Lung Inflammation in Mice
    Kastratovic, Nikolina
    Markovic, Vladimir
    Harrell, Carl Randall
    Arsenijevic, Aleksandar
    Stojanovic, Milica Dimitrijevic
    Djonov, Valentin
    Volarevic, Vladislav
    [J]. NICOTINE & TOBACCO RESEARCH, 2024, 26 (06) : 704 - 714
  • [44] Immunological and toxicological risk assessment of e-cigarettes
    Kaur, Gagandeep
    Pinkston, Rakeysha
    Mclemore, Benathel
    Dorsey, Waneene C.
    Batra, Sanjay
    [J]. EUROPEAN RESPIRATORY REVIEW, 2018, 27 (147)
  • [45] Elevated Cellular Oxidative Stress in Circulating Immune Cells in Otherwise Healthy Young People Who Use Electronic Cigarettes in a Cross-Sectional Single-Center Study: Implications for Future Cardiovascular Risk
    Kelesidis, Theodoros
    Tran, Elizabeth
    Arastoo, Sara
    Lakhani, Karishma
    Heymans, Rachel
    Gornbein, Jeffrey
    Middlekauff, Holly R.
    [J]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2020, 9 (18):
  • [46] Flavoring Compounds Dominate Toxic Aldehyde Production during E-Cigarette Vaping
    Khlystov, Andrey
    Samburova, Vera
    [J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 50 (23) : 13080 - 13085
  • [47] Response of the microbiome-gut-brain axis in Drosophila to amino acid deficit
    Kim, Boram
    Kanai, Makoto I.
    Oh, Yangkyun
    Kyung, Minsoo
    Kim, Eun-Kyoung
    Jang, In-Hwan
    Lee, Ji-Hoon
    Kim, Sang-Gyu
    Suh, Greg S. B.
    Lee, Won-Jae
    [J]. NATURE, 2021, 593 (7860) : 570 - +
  • [48] Claudins, VEGF, Nrf2, Keap1, and Nonspecific Airway Hyper-Reactivity Are Increased in Mice Co-Exposed to Allergen and Acrolein
    Kim, Byeong-Gon
    Lee, Pureun-Haneul
    Lee, Sun-Hye
    Hong, Jisu
    Jang, An-Soo
    [J]. CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 32 (01) : 139 - 145
  • [49] The combination of propylene glycol and vegetable glycerin e-cigarette aerosols induces airway inflammation and mucus hyperconcentration
    Kim, Michael D.
    Chung, Samuel
    Baumlin, Nathalie
    Qian, Jian
    Montgomery, Robert N.
    Sabater, Juan
    Berkland, Cory
    Salathe, Matthias
    [J]. SCIENTIFIC REPORTS, 2024, 14 (01)
  • [50] Daily exposure to formaldehyde and acetaldehyde and potential health risk associated with use of high and low nicotine e-liquid concentrations
    Kosmider, Leon
    Cox, Sharon
    Zaciera, Marzena
    Kurek, Jolanta
    Goniewicz, Maciej L.
    McRobbie, Hayden
    Kimber, Catherine
    Dawkins, Lynne
    [J]. SCIENTIFIC REPORTS, 2020, 10 (01)