The Impact of Metabolic and Bariatric Surgery on Diabetic Kidney Disease in Patients with Type 2 Diabetes: A Systematic Review and Meta-analysis

被引：0
作者：
Einafshar, Negar [1 ]
Esparham, Ali [2 ]
Moghani, Mahta Shari'at [1 ]
Radboy, Mahsa [1 ]
Ghamari, Mohammad Javad [3 ]
Zandbaf, Tooraj [3 ]
机构：
[1] Islamic Azad Univ, Fac Med, Innovat Med Res Ctr, Mashhad Med Sci, Mashhad, Iran
[2] Mashhad Univ Med Sci, Student Res Comm, Fac Med, Mashhad, Iran
[3] Islamic Azad Univ, Fac Med, Dept Gen Surg, Mashhad Med Sci, Mashhad, Iran
来源：
OBESITY SURGERY | 2025年 / 35卷 / 01期
关键词：
Metabolic and bariatric surgery; Diabetes mellitus; Nephropathy; Albuminuria; Urinary albumin excretion; Y GASTRIC BYPASS; WEIGHT-LOSS; MEDICAL-MANAGEMENT; RENAL-FUNCTION; LIFE-STYLE; NEPHROPATHY; OBESITY; OUTCOMES; COMPLICATIONS; ALBUMINURIA;
D O I：
10.1007/s11695-024-07612-8
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
We aimed to determine the effect of metabolic and bariatric surgery (MBS) on the improvement of diabetic nephropathy (DN) in patients with obesity and type 2 diabetes (T2DM). A systematic search was performed in the PubMed, Embase, Scopus, and Web of Science databases. Meta-analysis of 31 studies with 2594 patients showed that urine albumin-to-creatinine ratio (UACR) was significantly reduced with a mean difference of - 28.19 mg/g (95% CI - 41.17, - 15.21, P-value < 0.001). In addition, subgroup analysis of studies showed a significant decrease after Roux-en-Y gastric bypass (RYGB) but not after sleeve gastrectomy (SG). These results suggest that MBS may lead to better kidney function and improvement in DN.
引用
收藏
页码：329 / 340
页数：12
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