The impact of a fracture liaison service for patients with femoral fractures on subsequent fractures and mortality: focusing on systematic literature review and metaanalysis

被引：0

作者：

Kim, Min Soo ^{[1
]}

Yang, Jeong-Min ^{[1
]}

Cha, Yonghan ^{[2
]}

Kim, Seung Hoon ^{[3
]}

Park, Minah ^{[3
]}

Kim, Jae-Hyun ^{[4
,5
]}

机构：

[1] Dankook Univ, Dept Publ Hlth, Gen Grad Sch, Cheonan, South Korea

[2] Eulji Univ, Daejeon Eulji Med Ctr, Dept Orthoped Surg, Sch Med, Daejeon, South Korea

[3] Soonchunhyang Univ, Coll Med, Dept Ophthalmol, Cheonan Si, Chungcheongnam, South Korea

[4] Dankook Univ, Inst Hlth & Med Policy, Cheonan Si, Chungcheongnam, South Korea

[5] Dankook Univ, Coll Hlth Sci, Dept Hlth Adm, Cheonan Si, Chungcheongnam, South Korea

来源：

ARCHIVES OF OSTEOPOROSIS | 2025年 / 20卷 / 01期

关键词：

Femur fracture; Fracture liaison service; Subsequent fracture; Mortality; Coordinator; HIP FRACTURE; MULTIDISCIPLINARY APPROACH; PREVENTION SERVICE; CARE; SURGERY; IMPROVE; REDUCE; NURSE; OLDER;

D O I：

10.1007/s11657-025-01505-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The purpose of this study is to scientifically and systematically investigate the clinical effectiveness of a fracture liaison service (FLS) for patients with femoral fractures. Methods The international databases Ovid-MEDLINE, EMBASE, and The Cochrane Library and the Korean databases KISS, RISS, KoreaScience, Koreamed, and Kmbase were used. Risk of bias assessment was conducted at the study design level, and meta-analysis utilized both random-effects and fixed-effects models, along with subgroup analysis. Results From the 32 selected articles, 14 articles related to subsequent fracture and 18 articles related to mortality were included in the meta-analysis. As a result of the meta-analysis, the risk of subsequent fracture in the group that participated in the fracture liaison service was 46% lower than that in the non-participated group, and this difference was statistically significant (RR = 0.54, 95% CI = 0.50-0.59). The risk of death in the group that participated in the FLS was 17% lower than that in the non-participating group, and this difference was not statistically significant as well (RR = 0.83, 95% CI = 0.67-1.03). As a result of subgroup analysis, there was a statistically significant difference in the reduction of subsequent fracture in the clinical outcomes, and there was a significant difference in mortality in the intervention follow-up period and clinical outcomes. Conclusion The global implementation of FLS has played a crucial role in enhancing the clinical management and treatment of patients with femoral fractures, contributing to a decrease in subsequent fracture and mortality. This indicates the significant role of FLS in minimizing the disease burden associated with femoral fractures worldwide.

引用

页数：18