Canine lymphoma in Croatia: a fourteen-year retrospective study

被引：0
作者：
Eraghi, Vida [1 ]
Zagradisnik, Lidija Medven [1 ]
Matasovic, Mavro [2 ]
Vlahovic, Dunja [1 ]
Huber, Doroteja [1 ]
Kurilj, Andrea Gudan [1 ]
Sostaric-Zuckermann, Ivan-Conrado [1 ]
Artukovic, Branka [1 ]
Buhin, Ivana Mihokovic [1 ]
Cipric, Iva [1 ]
Hohsteter, Marko [3 ]
机构：
[1] Univ Zagreb, Fac Vet Med, Dept Vet Pathol, Zagreb, Croatia
[2] Vet Point, Vet Practice, Zagreb, Croatia
[3] Bioinst Doo, Cakovec, Croatia
来源：
BMC VETERINARY RESEARCH | 2025年 / 21卷 / 01期
关键词：
Canine lymphoma; Croatia; Retrospective study; Cytology; Immunohistochemistry; Immunocytochemistry; MULTICENTRIC LYMPHOMA; MALIGNANT-LYMPHOMA; DOGS; CELL; CLASSIFICATION; ASSOCIATION; PREVALENCE;
D O I：
10.1186/s12917-025-04634-x
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
BackgroundLymphoma is the most prevalent hematopoietic system tumor in dogs and holds significant clinical importance in veterinary medicine. However, the epidemiology of canine lymphoma in Croatia remains understudied. This retrospective study aims to describe the predominant lymphoma types in this population over 14 years and evaluate associations with sex, breed, and age.ResultsAmong 28,681 canine cases referred to the Department of Veterinary Pathology, University of Zagreb, from 2009 to 2023, a total of 374 cases (1.30%) were diagnosed with lymphoma. Of these, 282 cases (75.40%) were purebred dogs, with the most affected breeds being Golden Retrievers (23, 6.15%), Labrador Retrievers (23, 6.15%), German Shepherds (14, 3.74%), and Boxers (14, 3.74%). Bullmastiffs (8.14%) had the highest number of lymphoma diagnoses among the referred breeds, followed by Airedale Terriers (6.67%) and German Shepherds (5.09%). The Maltese, though a popular breed, showed a low lymphoma rate of 0.40%, indicating no notable predisposition. Multicentric lymphoma (59, 53.64%) was the most common anatomical classification, followed by cutaneous (33, 30.00%) and alimentary lymphoma (13, 11.82%). The mean age at diagnosis was 8.27 +/- 3.07 years, with most cases occurring between 5 and 10 years (207, 55.35%). Males (216, 57.75%) were more frequently affected than females (158, 42.24%), except among Golden Retrievers, where 69.56% of cases were female.ConclusionOur study reveals that the distribution of dogs with lymphomas, including type and anatomical classification, in terms of breed, sex and age, is consistent with existing literature, except in the cases of Golden Retrievers, Basset Hounds, and Scottish Terriers. Further molecular and environmental studies are recommended.
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页数：7
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