Spatial mapping of Alzheimer's disease across genetic subtypes

被引：0
作者：
Nott, Alexi [1 ,2 ]
Holtman, Inge R. [3 ]
机构：
[1] Imperial Coll London, Dept Brain Sci, London, England
[2] Imperial Coll London, UK Dementia Res Inst, London, England
[3] Univ Groningen, Univ Med Ctr Groningen, Dept Biomed Sci, Sect Mol Neurobiol, Groningen, Netherlands
来源：
NATURE GENETICS | 2024年 / 56卷 / 12期
基金：
英国医学研究理事会;
关键词：
MECHANISMS;
D O I：
10.1038/s41588-024-01895-4
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Alzheimer's disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and subtype-specific cellular and molecular mechanisms of Alzheimer's disease.
引用
收藏
页码：2592 / 2593
页数：2
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