Association between fine particulate matter (PM2.5) and atopic dermatitis-a systematic review

被引:0
|
作者
Weslock, Noah [1 ]
Drew, Delaney [1 ]
Palanichami, Deepak [1 ]
La, Anthony [1 ]
Shoctor, Hannah [1 ]
Amir, Alkhafaji [1 ]
Ramdass, Prakash [1 ]
Mitchell, Kerry [1 ]
机构
[1] St Georges Univ, Sch Med, Dept Publ Hlth & Prevent Med, St Georges, Grenada
关键词
EXPOSURE; RISKS;
D O I
10.1186/s12982-025-00502-z
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
IntroductionParticulate matter (PM2.5) is associated with numerous adverse outcomes due in part to its ability to enter systemic circulation. Though its impact on the respiratory and cardiovascular systems is well studied, focus is now being placed on additional organ systems that are also associated with significant morbidity. Thus, this systematic review aims to summarize the available data on the association between particulate matter (PM2.5) exposure and atopic dermatitis (AD); and to describe the likely pathophysiological links.MethodsA literature search was conducted using PubMed, ScienceDirect, and SCOPUS. Studies on the prevalence or incidence of atopic dermatitis as an outcome, with exposure to particulate matter (PM2.5) as a predictor were included. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The risk of bias in the selected studies was assessed using the QUADAS-2 tool.ResultsEleven studies met the specified inclusion criteria. All found statistical significance of an increase in AD in some subgroups, though not all found significance in the general population. Outcomes measured included the number of visits to clinics and hospitals or changes in AD symptoms to determine if AD was worsened. Males, children, and the elderly were noted in multiple studies as having an increased risk for worsen AD. Environmental factors were also seen to modulate the effects of PM2.5 concentrations, specifically humidity levels due to seasonal changes and maintained indoor temperatures.ConclusionPM2.5 was linked with a statistically and clinically significant increase in AD, with children, older people, and biological males at increased risk. This link is likely related to epidermal dysfunction, hormonal dysregulation, and heightened immune responses. These findings highlight the impact of air pollution exposure on skin disease morbidity and highlight the need for a high index of suspicion for environmental exposures when diagnosing and treating skin diseases.
引用
收藏
页数:15
相关论文
共 50 条
  • [1] The relationship between fine particulate matter (PM2.5) and schizophrenia severity
    Rika Eguchi
    Daisuke Onozuka
    Kouji Ikeda
    Kenji Kuroda
    Ichiro Ieiri
    Akihito Hagihara
    International Archives of Occupational and Environmental Health, 2018, 91 : 613 - 622
  • [2] The relationship between fine particulate matter (PM2.5) and schizophrenia severity
    Eguchi, Rika
    Onozuka, Daisuke
    Ikeda, Kouji
    Kuroda, Kenji
    Ieiri, Ichiro
    Hagihara, Akihito
    INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 2018, 91 (05) : 613 - 622
  • [3] A review of respirable fine particulate matter (PM2.5)-induced brain damage
    Li, Wei
    Lin, Guohui
    Xiao, Zaixing
    Zhang, Yichuan
    Li, Bin
    Zhou, Yu
    Ma, Yong
    Chai, Erqing
    FRONTIERS IN MOLECULAR NEUROSCIENCE, 2022, 15
  • [4] Association of fine particulate matter (PM2.5) exposure and chronic kidney disease outcomes: a systematic review and meta-analysis
    Wathanavasin, Wannasit
    Banjongjit, Athiphat
    Phannajit, Jeerath
    Eiam-Ong, Somchai
    Susantitaphong, Paweena
    SCIENTIFIC REPORTS, 2024, 14 (01)
  • [5] Fine particulate matter (PM2.5) in China at a city level
    Zhang, Yan-Lin
    Cao, Fang
    SCIENTIFIC REPORTS, 2015, 5
  • [6] Fine particulate matter (PM2.5) in China at a city level
    Yan-Lin Zhang
    Fang Cao
    Scientific Reports, 5
  • [7] Fine Particulate Matter (PM2.5) and Chronic Kidney Disease
    Zhang, Yilin
    Liu, Dongwei
    Liu, Zhangsuo
    REVIEWS OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, VOL 254, 2021, 254 : 183 - 215
  • [8] Toxicological Effects of Fine Particulate Matter (PM2.5): Health Risks and Associated Systemic Injuries—Systematic Review
    Amanda Garcia
    Eduarda Santa-Helena
    Anna De Falco
    Joaquim de Paula Ribeiro
    Adriana Gioda
    Carolina Rosa Gioda
    Water, Air, & Soil Pollution, 2023, 234
  • [9] An association between fine particulate matter (PM2.5) levels and emergency ambulance dispatches for cardiovascular diseases in Japan
    Ichiki, Toshihiro
    Onozuka, Daisuke
    Kamouchi, Masahiro
    Hagihara, Akihito
    INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 2016, 89 (08) : 1329 - 1335
  • [10] Effect modification by statin use status on the association between fine particulate matter (PM2.5) and cardiovascular mortality
    Bai, Li
    Kwong, Jeffrey C.
    Kaufman, Jay S.
    Benmarhnia, Tarik
    Chen, Chen
    van Donkelaar, Aaron
    Martin, Randall, V
    Kim, Jinhee
    Lu, Hong
    Burnett, Richard T.
    Chen, Hong
    INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2024, 53 (04)