Effectiveness of the modified TaWai mobile application for reporting adverse drug reaction in Lao PDR: a cluster randomized controlled trial

被引：0

作者：

Mongkhonmath, Niphonh ^{[1
]}

Olson, Phayom Sookaneknun ^{[2
,3
]}

Puttarak, Panupong ^{[4
,5
]}

Keokinnaly, Soulyvanh ^{[6
]}

Sawangjit, Ratree ^{[7
]}

机构：

[1] Mahasarakham Univ, Fac Pharm, Dept Clin Pharm, Maha Sarakham, Thailand

[2] Mahasarakham Univ, Fac Pharm, Int Primary Care Practice Res Unit, Maha Sarakham, Thailand

[3] UCSI Univ, Fac Pharmaceut Sci, 1, Jalan UCSI, UCSI Hts, Cheras, Kuala Lumpur 56000, Malaysia

[4] Prince Songkla Univ, Fac Pharmaceut Sci, Dept Pharmacognosy & Pharmaceut Bot, Hat Yai 90110, Thailand

[5] Prince Songkla Univ, Fac Pharmaceut Sci, Innovat Unit Consumer Protect Healthcare Prod, TaWai Hlth Unit, Hat Yai 90110, Thailand

[6] Minist Hlth, Hosp Pharm Management Div, Lao PDR, Viangchan, Laos

[7] Mahasarakham Univ, Fac Pharm, Dept Clin Pharm, Clin Trials & Evidence Based Synth Res Unit CTEBs, Maha Sarakham 44150, Thailand

来源：

SCIENTIFIC REPORTS | 2024年 / 14卷 / 01期

关键词：

TaWai mobile App; ADR reporting; Pharmacovigilance; Low/middle-income countries; Lao PDR; EDUCATIONAL INTERVENTION; PHARMACOVIGILANCE;

D O I：

10.1038/s41598-024-82474-9

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Spontaneous adverse drug reactions (ADRs) reporting by health care professionals (HCPs) plays a vital role in pharmacovigilance (PV). However, under-reporting remain a major challenge worldwide, especially in low and middle-income countries, including Lao PDR. This cluster-randomized controlled trial evaluated the effectiveness of the modified TaWai mobile app for ADR reporting compared with the usual practice in hospitals. Two tertiary hospitals in Lao PDR (cluster units) were randomized into two groups: the intervention group (16 HCPs), which used the modified TaWai mobile app along with an educational workshop, and the control group (18 HCPs), which followed usual practice with the same educational workshop. The intervention group reported more ADR cases (28 vs. 3), and produced a higher number of high-quality reports (28 vs. 2) than the control group. The modified TaWai mobile app was highly rated by all participating HCPs. Questionnaire responses indicated that the tool is user-friendly, time-efficient, and well-suited for ADR reporting in hospitals in Lao PDR. In conclusion, these findings highlight the potential of the modified TaWai mobile app to enhance ADR reporting practices in hospitals, and its features make it a promising solution for strengthening PV in Lao PDR and similar settings.

引用

页数：13