Epidemiological disease burden and annual, nationwide health insurance treatment cost of female infertility based on real-world health insurance claims data in Hungary

被引:0
作者
Dalma Pónusz-Kovács [1 ]
Tímea Csákvári [2 ]
Luca Fanni Sántics-Kajos [1 ]
Diána Elmer [2 ]
Róbert Pónusz [1 ]
Bettina Kovács [2 ]
Ákos Várnagy [1 ]
Kálmán Kovács [2 ]
József Bódis [1 ]
Imre Boncz [2 ]
机构
[1] Faculty of Health Sciences, Institute for Health Insurance, University of Pécs, 7621 Vörösmarty Utca 3, Pécs
[2] National Laboratory On Human Reproduction, University of Pécs, 7624 Ifjúság Utca 20, Pécs
[3] Department of Obstetrics and Gynecology, Medical School, Clinical Center, University of Pécs, 7624 Édesanyák Útja 17, Pécs
关键词
Cost; Epidemiology; Female infertility; Hungary; Prevalence;
D O I
10.1186/s12913-025-12348-x
中图分类号
学科分类号
摘要
Background: Infertility affects more than 50 million couples worldwide, resulting in a significant burden on individuals and society. Its prevalence ranges from 8–12% among developed countries. The growing number of patients poses an increasing challenge to the healthcare system and its funding. Our quantitative, descriptive, and cross-sectional study aimed to analyze the prevalence and annual nationwide health insurance treatment cost of female infertility in Hungary in 2019. Methods: We used claims data obtained from the Hungarian National Health Insurance Fund Administration (NHFIA). The number of patients, total and age-specific prevalence, annual health insurance expenditure, and the distribution of costs by age group were evaluated. Infertility was determined according to the World Health Organization International Classification of Diseases codes (N.97.0, N97.1, N97.2, N97.3, N97.4, N97.8, and N97.9) and the utilization of each healthcare service type. During the study descriptive statistics, correlation analysis and t-test were used. Results: In 2019, the NHIFA spent a total of 7.2 billion HUF (22.2 million EUR) on female infertility treatment in Hungary (33,151 women in outpatient care). The most significant costs were related to inpatient care (4.1 billion HUF, 12.7 million EUR). The highest number of patients and prevalence (650.4 per 100,000 women) were found in outpatient care. In inpatient care, the prevalence is substantially lower (206.7 per 100,000 women). Regardless of its type, female infertility mainly affects patients in the 30–39 years age group (number of patients: 18,156 women). The average annual health insurance expenditure per capita was 1,083 EUR. Conclusions: Reproductive health education, prevention, and medical screening play inevitable roles in the early stages of reproductive life to reduce the risk of infertility and decrease treatment costs. © The Author(s) 2025.
引用
收藏
相关论文
共 74 条
  • [1] Ely D.M., Hamilton B.E., Trends in fertility and mother's age at first birth among rural and metropolitan counties: United States, 2007–2017, NCHS Data Brief, 323, pp. 1-8, (2018)
  • [2] Eijkemans M.J., van Poppel F., Habbema D.F., Smith K.R., Leridon H., te Velde E.R., Too old to have children? Lessons from natural fertility populations, Hum Reprod, 6, pp. 1304-1312, (2014)
  • [3] Szatmari A., Fejes Z., Kiraly I., Men's knowledge of male infertility and the possibilities for supporting therapy: risk factors and individual responses, Orv Hetil, 159, 31, pp. 1262-1268, (2018)
  • [4] HCSO): Live births by main characteristics of mother and newborn, Hungary
  • [5] Vander Borght M., Wyns C., Fertility and infertility: definition and epidemiology, Clin Biochem, 62, pp. 2-10, (2018)
  • [6] Lakatos E., Papay N., Adam S., Balog P., Theoretical models and paradigms regarding infertility, Pszichológia, 34, 3, pp. 261-287, (2014)
  • [7] Garolla A., Pizzol D., Carosso A.R., Borini A., Ubaldi F.M., Calogero A.E., Et al., Practical Clinical and Diagnostic Pathway for the Investigation of the Infertile Couple, Front Endocrinol (Lausanne), 11, (2021)
  • [8] Jose-Miller A.B., Boyden J.W., Frey K.A., Infertility, Am Fam Physician, 75, 6, pp. 849-856, (2007)
  • [9] Woods B.M., Bray L.A., Campbell S., Holland A., Mrug S., Ladores S., A review of the psychometric properties and implications for the use of the fertility quality of life tool, Health Qual Life Outcomes, 21, 1, (2023)
  • [10] Boivin J., Bunting L., Collins J.A., Nygren K.G., International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care, Hum Reprod, 22, 6, pp. 1506-1512, (2007)