The Arabidopsis F-box protein FBS associated with the helix-loop-helix transcription factor FAMA involved in stomatal immunity

被引：0
作者：
Zhang, Chunxia [1 ,3 ]
Yue, Junling [1 ,2 ]
Li, Shi [1 ,2 ]
Zuo, Chaoran [1 ,2 ]
Li, Yi [1 ,2 ]
He, Qixiumei [1 ,2 ]
Le, Jie [1 ,2 ,3 ]
机构：
[1] Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] China Natl Bot Garden, Beijing 100093, Peoples R China
来源：
PLANT MOLECULAR BIOLOGY | 2025年 / 115卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Stomatal immunity; FBS; FAMA; Pathogen attack; GUARD-CELLS; INNATE IMMUNITY; SALICYLIC-ACID; EXPRESSION; GENE; DIFFERENTIATION; PATHWAY; COMPLEX;
D O I：
10.1007/s11103-025-01577-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Stomatal pores serve as primary entry points for pathogen invasion. Stomatal closure is a crucial strategy that plants employ to counter pathogen attack. Here, we report that F-BOX STRESS-INDUCED (FBS) is essential for modulating stomatal closure, thereby enhancing resistance to bacteria in Arabidopsis thaliana. The fbs2-1 fbs3-1 fbs4-2 triple mutant displayed increased susceptibility to Pseudomonas syringae pv. tomato (PstDC3000) due to impaired stomatal closure. Additionally, FBS4 interacts with and degrades the basic helix-loop-helix (bHLH) transcription factor FAMA. Both the fama-1 single mutant plants and the fama-1 fbs2-1 fbs3-1 fbs4-2 quadruple mutant plants exhibited resistance to PstDC3000 inoculation. Furthermore, the expression levels of abscisic acid (ABA)-responsive genes RD29A, RD29B, ABI2, and CIPK25 were altered in the fbs2-1 fbs3-1 fbs4-2 and fama-1 mutant plants. Collectively, our data demonstrate that FBS, in association with FAMA, plays an important role in pathogen invasion by influencing ABA signaling-related stomatal closure.
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页数：12
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