Approximate Solutions of a General Stochastic Velocity-Jump Model Subject to Discrete-Time Noisy Observations

被引:0
|
作者
Ceccarelli, Arianna [1 ]
Browning, Alexander P. [1 ]
Baker, Ruth E. [1 ]
机构
[1] Univ Oxford, Math Inst, Woodstock Rd, Oxford OX2 6GG, England
基金
英国工程与自然科学研究理事会;
关键词
Generalised velocity-jump model; Continuous-time Markov chain; Single-agent tracking data; Probability density function; Approximate likelihood; RANDOM-WALK; TRANSPORT; MOVEMENT; DISPERSAL;
D O I
10.1007/s11538-025-01437-x
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Advances in experimental techniques allow the collection of high-resolution spatio-temporal data that track individual motile entities over time. These tracking data motivate the use of mathematical models to characterise the motion observed. In this paper, we aim to describe the solutions of velocity-jump models for single-agent motion in one spatial dimension, characterised by successive Markovian transitions within a finite network of n states, each with a specified velocity and a fixed rate of switching to every other state. In particular, we focus on obtaining the solutions of the model subject to noisy, discrete-time, observations, with no direct access to the agent state. The lack of direct observation of the hidden state makes the problem of finding the exact distributions generally intractable. Therefore, we derive a series of approximations for the data distributions. We verify the accuracy of these approximations by comparing them to the empirical distributions generated through simulations of four example model structures. These comparisons confirm that the approximations are accurate given sufficiently infrequent state switching relative to the imaging frequency. The approximate distributions computed can be used to obtain fast forwards predictions, to give guidelines on experimental design, and as likelihoods for inference and model selection.
引用
收藏
页数:28
相关论文
共 3 条
  • [1] Stability of stochastic discrete-time piecewise homogeneous Markov jump systems with time delay and impulsive effects
    Wang, Pengfei
    Wang, Weiye
    Su, Huan
    Feng, Jiqiang
    NONLINEAR ANALYSIS-HYBRID SYSTEMS, 2020, 38
  • [2] Asynchronous Sliding-Mode Control for Discrete-Time Networked Hidden Stochastic Jump Systems With Cyber Attacks
    Qi, Wenhai
    Zhang, Ning
    Zong, Guangdeng
    Su, Shun-Feng
    Cao, Jinde
    Cheng, Jun
    IEEE TRANSACTIONS ON CYBERNETICS, 2024, 54 (03) : 1934 - 1946
  • [3] Stabilization of multi-group models with multiple dispersal and stochastic perturbation via feedback control based on discrete-time state observations
    Luo, Tianjiao
    APPLIED MATHEMATICS AND COMPUTATION, 2019, 354 : 396 - 410