Novel Eu(III) and Tb(III) complexes bearing carboxamide ligand: antiproliferative activity, photoluminescence properties, and thermogravimetric studies

被引：0

作者：

Sarioglu, Ahmet Oral ^{[1
]}

Sogukomerogullari, Hatice Gamze ^{[2
]}

Kose, Aysegul ^{[3
]}

Akkoc, Senem ^{[4
,5
]}

Sonmez, Mehmet ^{[6
]}

Morcali, Mehmet Hakan ^{[1
]}

机构：

[1] Gaziantep Univ, Naci Topcuoglu Vocat Sch, Dept Chem & Chem Proc Technol, TR-27310 Gaziantep, Turkiye

[2] Gaziantep Univ, Hlth Serv Vocat Sch, Med Serv & Tech Dept, TR-27310 Gaziantep, Turkiye

[3] Kahramanmaras Istiklal Univ, Elbistan Vocat Sch, Dept Property Protect & Safety, Kahramanmaras, Turkiye

[4] Suleyman Demirel Univ, Fac Pharm, Dept Basic Pharmaceut Sci, Isparta, Turkiye

[5] Bahcesehir Univ, Fac Engn & Nat Sci, Istanbul, Turkiye

[6] Gaziantep Univ, Fac Sci & Arts, Dept Chem, TR-27310 Gaziantep, Turkiye

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2024年 / 21卷 / 12期

关键词：

beta-diketones; Carboxamide lanthanide complexes; Photoluminescence properties; Antiproliferative activity; Thermogravimetric analysis; LANTHANIDE COMPLEXES; CRYSTAL-STRUCTURES; MOLECULAR DOCKING; METAL-COMPLEXES; DERIVATIVES; ACID; FLUORESCENCE; DNA;

D O I：

10.1007/s13738-024-03112-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, beta-diketone derivative new carboxamide Eu(III) and Tb(III) lanthanide complexes were synthesized and characterized by FT-IR, elemental analysis, UV-Vis, and molar conductivity techniques. There is no electrolytic conductivity in the compounds. Moreover, the photoluminescence properties and thermal behavior of the synthesized lanthanide complexes were investigated. Photoluminescence data revealed that the Tb(III) complex showed metal-based f-f transitions. The beta-diketone derivative carboxamide ligand exhibited as antenna that transmitted the excited energy to the emission energy levels of the Tb(III) ion. These metal complexes were screened in two different common cancer cell lines and a human normal embryonic kidney cell line for 48 h. The results showed that these complexes have more antiproliferative activities in the colon cancer cell line compared to the lung cancer cell line.

引用

页码：2923 / 2931

页数：9

共 63 条

[1] Synthesis, crystal structure, NMR and near infra-red luminescence studies of nine-coordinate Nd and Yb complexes based on fluorinated β-diketone and a tridentate antenna chromophore, 2, 4, 6-Tris-(2-pyridyl)-s-triazine [J].