Non-invasive brain stimulation to modulate neural activity in Parkinson's disease

被引：1

作者：

Bange, Manuel ^{[1
]}

Helmich, Rick C. G. ^{[2
,3
]}

Shukla, Aparna A. Wagle ^{[4
]}

Deuschl, Guenther ^{[5
]}

Muthuraman, Muthuraman ^{[1
,6
]}

机构：

[1] Univ Augsburg, Inst Comp Sci Informat Med Technol, Augsburg, Germany

[2] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Ctr Cognit Neuroimaging, Nijmegen, Netherlands

[3] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Ctr Expertise Parkinson & Movement Disorders, Dept Neurol, Nijmegen, Netherlands

[4] Univ Florida, Norman Fixel Inst Neurol Dis, Gainesville, FL USA

[5] Univ Kiel, Dept Neurol, UKSH Kiel Campus, Kiel, Germany

[6] Univ Clin Wurzburg, Dept Neurol, Neural Engn Signal Analyt & Artificial Intelligenc, Wurzburg, Germany

来源：

NPJ PARKINSONS DISEASE | 2025年 / 11卷 / 01期

关键词：

TRANSCRANIAL MAGNETIC STIMULATION; SUBTHALAMIC NUCLEUS STIMULATION; MOTOR-CORTICAL OSCILLATIONS; FUNCTIONAL CONNECTIVITY; ELECTRICAL-STIMULATION; DIAGNOSTIC-CRITERIA; MOVEMENT-DISORDERS; BETA BURSTS; CORTEX; STATE;

D O I：

10.1038/s41531-025-00908-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Despite its potential to modulate brain and network activity, non-invasive brain stimulation is not yet clinically applied for treating Parkinson's disease. We here review recent findings that illustrate how various non-invasive stimulation techniques can modify pathological and compensatory activities. Due to unavoidable heterogeneities and low effect sizes of the reviewed studies, a deeper understanding of the mechanisms of action will be critical for refining clinical effectiveness and generating consistent results.

引用

页数：14

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