A Facile Synthesis and Docking Studies of 1,2,4-Triazolo[3,4-b][1,3,4]oxadiazole Derivatives

被引:0
作者
Hanumanthugari, Vindhya [1 ]
Syeda, Asra Banu [2 ]
Pittala, Bhaskar [3 ]
Eppakayala, Laxminarayana [3 ]
Dholvan, Mohan [3 ]
Sambaru, Kalyani [1 ]
机构
[1] Mahtama Gandhi Univ, Anneparthy 508254, India
[2] Jazan Univ, Coll Sci, Dept Phys Sci, Chem Div, Jazan 45142, Saudi Arabia
[3] Sreenidhi Inst Sci & Technol, Ghatkesar 501301, India
关键词
oxadiazole; triazole; docking studies; 1,3,4-OXADIAZOLE DERIVATIVES; PHARMACOLOGICAL EVALUATION; BASES;
D O I
10.1134/S0012500824600846
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple and efficient method was developed to synthesize triazole, oxadiazole derivatives. The newly synthesized compounds were confirmed by their IR, H-1 and C-13 NMR, and mass spectral data. Molecular docking studies have been performed for all the derivatives.
引用
收藏
页码:87 / 93
页数:7
相关论文
共 24 条
  • [1] Synthesis and in vitro anti-tumor activity of new oxadiazole thioglycosides
    Abu-Zaied, M. A.
    El-Telbani, E. M.
    Elgemeie, G. H.
    Nawwar, G. A. M.
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (01) : 229 - 235
  • [2] Oxadiazole mannich bases: Synthesis and antimycobacterial activity
    Ali, Mohamed Ashraf
    Shaharyar, Mohammad
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (12) : 3314 - 3316
  • [3] Bala S., 2012, Int. J. Pharm. Sci. Rev. Res, V17, P84
  • [4] Synthesis and in vitro antiproliferative activity of new 1,3,4-oxadiazole derivatives possessing sulfonamide moiety
    El-Din, Mahmoud M. Gamal
    El-Gamal, Mohammed I.
    Abdel-Maksoud, Mohammed S.
    Yoo, Kyung Ho
    Oh, Chang-Hyun
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 90 : 45 - 52
  • [5] Synthesis, Anti-Microbial, and Cytotoxic Activities Evaluation of Some New Pyrido[2,3-d]Pyrimidines
    Elsaedany, Samir Kamel
    Zein, Mohamed AbdEllatif
    AbedelRehim, Elsayed Mohmoud
    Keshk, Reda Mohammed
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2016, 53 (05) : 1534 - 1543
  • [6] Synthesis and antimicrobial studies of a new series of 2-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}-5-substituted-1,3,4-oxadiazoles
    Gaonkar, S. L.
    Rai, K. M. L.
    Prabhuswamy, B.
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2006, 41 (07) : 841 - 846
  • [7] Synthesis and biological evaluation of 3-(4-chlorophenyl)-4-substituted pyrazole derivatives
    Horrocks, P.
    Pickard, M. R.
    Parekh, H. H.
    Patel, S. P.
    Pathak, Ravindra B.
    [J]. ORGANIC & BIOMOLECULAR CHEMISTRY, 2013, 11 (29) : 4891 - 4898
  • [8] Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties
    Husain, Asif
    Ajmal, Mohammed
    [J]. ACTA PHARMACEUTICA, 2009, 59 (02) : 223 - 233
  • [9] Synthesis and in vitro microbiological evaluation of an array of biolabile 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides
    Kanagarajan, V.
    Thanusu, J.
    Gopalakrishnan, M.
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (04) : 1583 - 1589
  • [10] Photocatalytic Oxidative Heterocyclization of Semicarbazones: An Efficient Approach for the Synthesis of 1,3,4-Oxadiazoles
    Kapoorr, Ritu
    Singh, Sachchida N.
    Tripathi, Shubhangi
    Yadav, Lal Dhar S.
    [J]. SYNLETT, 2015, 26 (09) : 1201 - 1206