Availability of transcatheter aortic valve implantation across hospitals and differences in strategies and clinical outcomes in patients with severe aortic stenosis

被引：0

作者：

Takeji, Yasuaki ^{[1
,2
]}

Taniguchi, Tomohiko ^{[3
]}

Morimoto, Takeshi ^{[4
]}

Shirai, Shinichi ^{[5
]}

Kitai, Takeshi ^{[3
,6
]}

Tabata, Hiroyuki ^{[5
]}

Ohno, Nobuhisa ^{[7
]}

Murai, Ryosuke ^{[3
]}

Osakada, Kohei ^{[8
]}

Murata, Koichiro ^{[9
]}

Nakai, Masanao ^{[10
]}

Tsuneyoshi, Hiroshi ^{[11
]}

Tada, Tomohisa ^{[12
]}

Amano, Masashi ^{[6
]}

Watanabe, Shin ^{[2
]}

Shiomi, Hiroki ^{[2
]}

Watanabe, Hirotoshi ^{[13
]}

Yoshikawa, Yusuke ^{[14
]}

Nishikawa, Ryusuke ^{[2
]}

Obayashi, Yuki ^{[2
]}

Yamamoto, Ko ^{[5
]}

Toyofuku, Mamoru ^{[15
]}

Tatsushima, Shojiro ^{[15
]}

Kanamori, Norio ^{[16
]}

Miyake, Makoto ^{[17
]}

Nakayama, Hiroyuki ^{[18
]}

Nagao, Kazuya ^{[19
]}

Izuhara, Masayasu ^{[20
]}

Nakatsuma, Kenji ^{[21
]}

Inoko, Moriaki ^{[22
]}

Fujita, Takanari ^{[15
]}

Kimura, Masahiro ^{[23
]}

Ishii, Mitsuru ^{[24
]}

Usami, Shunsuke ^{[25
]}

Nakazeki, Fumiko ^{[26
]}

Togi, Kiyonori ^{[27
]}

Inuzuka, Yasutaka ^{[28
]}

Ando, Kenji ^{[5
]}

Komiya, Tatsuhiko ^{[29
]}

Ono, Koh ^{[2
]}

Minatoya, Kenji ^{[30
]}

Kimura, Takeshi ^{[13
]}

机构：

[1] Kanazawa Univ, Dept Cardiovasc Med, Grad Sch Med Sci, Kanazawa, Ishikawa, Japan

[2] Kyoto Univ, Grad Sch Med, Dept Cardiovasc Med, Kyoto, Japan

[3] Kobe City Med Ctr Gen Hosp, Dept Cardiovasc Med, Kobe, Hyogo, Japan

[4] Hyogo Med Univ, Dept Clin Epidemiol, Nishinomiya, Hyogo, Japan

[5] Kokura Mem Hosp, Dept Cardiol, Kitakyushu, Fukuoka, Japan

[6] Natl Cerebral & Cardiovasc Ctr, Dept Heart Failure & Transplantat, Suita, Osaka, Japan

[7] Kokura Mem Hosp, Div Cardiovasc Surg, Kitakyushu, Fukuoka, Japan

[8] Kurashiki Cent Hosp, Dept Cardiol, Kurashiki, Okayama, Japan

[9] Shizuoka City Shizuoka Hosp, Dept Cardiol, Shizuoka, Japan

[10] Shizuoka City Shizuoka Hosp, Dept Cardiovasc Surg, Shizuoka, Japan

[11] Shizuoka Prefectural Gen Hosp, Dept Cardiovasc Surg, Shizuoka, Japan

[12] Shizuoka Prefectural Gen Hosp, Dept Cardiol, Shizuoka, Japan

[13] Hirakata Kohsai Hosp, Dept Cardiol, 1-2-1 Fujisaka Higashi Machi, Hirakata, Osaka 5730153, Japan

[14] Natl Cerebral & Cardiovasc Ctr, Dept Biostat, Suita, Osaka, Japan

[15] Japanese Red Cross Wakayama Med Ctr, Dept Cardiol, Wakayama, Japan

[16] Shimada Gen Med Ctr, Div Cardiol, Shimada, Japan

[17] Tenri Hosp, Dept Cardiol, Tenri, Nara, Japan

[18] Hyogo Prefectural Amagasaki Gen Med Ctr, Dept Cardiol, Amagasaki, Hyogo, Japan

[19] Osaka Red Cross Hosp, Dept Cardiovasc Ctr, Osaka, Japan

[20] Kishiwada City Hosp, Dept Cardiol, Kishiwada, Japan

[21] Mitsubishi Kyoto Hosp, Dept Cardiol, Kyoto, Japan

[22] Kitano Hosp, Tazuke Kofukai Med Res Inst, Cardiovasc Ctr, Osaka, Japan

[23] Koto Mem Hosp, Dept Cardiol, Higashiomi, Japan

[24] Natl Hosp Org Kyoto Med Ctr, Dept Cardiol, Kyoto, Japan

[25] Kansai Elect Power Hosp, Dept Cardiol, Osaka, Japan

[26] Japanese Red Cross Otsu Hosp, Dept Cardiol, Otsu, Shiga, Japan

[27] Kindai Univ, Nara Hosp, Div Cardiol, Ikoma, Japan

[28] Shiga Gen Hosp, Dept Cardiol, Moriyama, Japan

[29] Kurashiki Cent Hosp, Dept Cardiovasc Surg, Kurashiki, Okayama, Japan

[30] Kyoto Univ, Grad Sch Med, Dept Cardiovasc Surg, Kyoto, Japan

来源：

CARDIOVASCULAR INTERVENTION AND THERAPEUTICS | 2025年 / 40卷 / 01期

关键词：

Aortic stenosis; Transcatheter aortic valve implantation; Surgical aortic valve replacement; REPLACEMENT;

D O I：

10.1007/s12928-024-01054-w

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There was a scarcity of data evaluating variations in treatment approaches and clinical outcomes for severe aortic stenosis (AS) between medical centers with and without availability of transcatheter aortic valve implantation (TAVI). Current study population was 2993 patients with severe AS enrolled in the CURRENT AS Registry-2 (2581 patients from 10 TAVI centers; 412 patients from 10 non-TAVI centers). TAVI centers more frequently opted for the initial aortic valve replacement (AVR) strategy compared to non-TAVI centers (60% and 40%, P<0.001). Among patients with the initial AVR strategy, TAVI centers disproportionately favored the initial TAVI strategy compared to non-TAVI centers (71% and 23%, P<0.001). No significant differences were observed in the risk of a composite of all-cause death or heart failure hospitalization between TAVI and non-TAVI centers in the entire study population (cumulative 3-year incidence: 32.0% and 31.0%, P=0.37; adjusted hazard ratios: 0.92, 95% confidence intervals: 0.74-1.15, P=0.45) or in conservative, initial AVR, initial surgical AVR, and initial TAVI strata. A substantial disparity exists in the treatment strategies for patients with severe AS between TAVI and non-TAVI centers. TAVI centers tended to perform AVR, particularly TAVI, earlier and more frequently. However, there was no discernible distinction in the risk of the composite of all-cause death or HF hospitalization between TAVI and non-TAVI centers. UMINID: UMIN000034169.

引用

页码：152 / 163

页数：12

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