The intraoperative SEEG and 18FDG-PET tailored temporal lobe resection (iSP-TR) for the tissue-spearing surgical treatment of drug-resistant mesial temporal lobe epilepsy: how we do it

被引:0
作者
Battista, Francesca [1 ]
Carrai, Riccardo [2 ]
Grippo, Antonello [2 ]
Della Puppa, Alessandro [3 ]
机构
[1] Careggi Univ Hosp, Dept Neurosurg, Florence, Italy
[2] Univ Florence, Careggi Hosp, Neuromuscular Skeletal Dept, Neurophysiopathol Unit, Florence, Italy
[3] Univ Florence, Careggi Univ Hosp, Dept Neurosurg, Dept Neurosci Drug Area & Child Hlth NEUROFARBA,Ps, Florence, Italy
关键词
Meningiomas; iSEEG; Epilepsy; Epilepsy surgery; FDG-PET; Temporal lobe epilepsy;
D O I
10.1007/s00701-025-06491-x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BackgroundFor drug-resistant mesial temporal lobe epilepsy (MTLE), surgery is recommended. There is no evidence of a seizure outcome advantage of temporal lobectomy over other strategies despite the high risks of this surgical procedure.MethodsWe describe a Temporal Resection guided by intraoperative stereo-electroencephalography (iSEEG) and the 18FluoroDeoxyGlucose PET (18FDG PET) (iSP-TR) to treat lesional MTLE. We avoided functional cortical areas using navigated Transcranial Magnetic Stimulation (nTMS).ConclusioniSP-TR allows for a spare brain parenchyma compared to temporal lobectomy without compromising seizure outcomes.
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页数:6
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