Successful corneal endothelium preservation in the management of epithelial downgrowth with 5-fluorouracil injections and membranectomy

被引:0
作者
Kam, Ka Wai [1 ,2 ,3 ]
Ma, Andre [1 ,2 ,3 ]
Ng, Joanna [4 ]
Choi, Paul [4 ]
Yip, Wilson Wai Kuen [1 ,2 ,3 ]
Young, Alvin L. [1 ,2 ,3 ]
机构
[1] Prince Wales Hosp, Dept Ophthalmol & Visual Sci, Shatin, 30 Ngan Shing St, Hong Kong, Peoples R China
[2] Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Shatin, Hong Kong, Peoples R China
[3] Alice Ho Miu Ling Nethersole Hosp, Dept Ophthalmol & Visual Sci, Taipo, Hong Kong, Peoples R China
[4] Chinese Univ Hong Kong, Dept Anat & Cellular Pathol, Shatin, Hong Kong, Peoples R China
关键词
Epithelial downgrowth; Cataract surgery; 5-Fluorouracil; Mitomycin-C; Methotrexate;
D O I
10.1186/s12886-024-03719-9
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
A 74-year-old Chinese man underwent extracapsular cataract extraction in his right eye and developed a translucent iris membrane 4 months later. He was treated with two intracameral 5-FU injections and membranectomy at 2 weeks apart. At one year following the second membranectomy, the patient maintained a clear cornea without residual or recurrent membrane, an endothelial cell density of 1072 cell/mm2, a visual acuity of 20/50 and a normal intraocular pressure. Our technique of using dispersive and cohesive viscoelastics in protecting the corneal endothelium from intracameral 5-FU, helped preserve corneal endothelial cells and maintain corneal clarity at one year after surgery.
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页数:7
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