European Society of Intensive Care Medicine guidelines on end of life and palliative care in the intensive care unit

被引：10

作者：

Kesecioglu, Jozef ^{[1
]}

Rusinova, Katerina ^{[2
,3
]}

Alampi, Daniela ^{[4
]}

Arabi, Yaseen M. ^{[5
,6
]}

Benbenishty, Julie ^{[7
]}

Benoit, Dominique ^{[8
,9
]}

Boulanger, Carole ^{[10
]}

Cecconi, Maurizio ^{[11
,12
]}

Cox, Christopher ^{[13
]}

van Dam, Marjel ^{[1
]}

van Dijk, Diederik ^{[1
]}

Downar, James ^{[14
,15
]}

Efstathiou, Nikolas ^{[16
]}

Endacott, Ruth ^{[17
]}

Galazzi, Alessandro ^{[18
]}

van Gelder, Fiona ^{[19
]}

Gerritsen, Rik T. ^{[20
]}

Girbes, Armand ^{[21
]}

Hawyrluck, Laura ^{[22
]}

Herridge, Margaret ^{[23
,24
]}

Hudec, Jan ^{[25
,26
,27
]}

Kentish-Barnes, Nancy ^{[28
]}

Kerckhoffs, Monika ^{[1
]}

Latour, Jos M. ^{[29
,30
,31
]}

Malaska, Jan ^{[26
,27
,32
,33
]}

Marra, Annachiara ^{[34
]}

Meddick-Dyson, Stephanie ^{[35
]}

Mentzelopoulos, Spyridon ^{[36
]}

Mer, Mervyn ^{[37
,38
]}

Metaxa, Victoria ^{[39
,40
]}

Michalsen, Andrej ^{[41
]}

Mishra, Rajesh ^{[42
]}

Mistraletti, Giovanni ^{[43
,44
]}

van Mol, Margo ^{[45
]}

Moreno, Rui ^{[46
,47
,48
]}

Nelson, Judith ^{[49
]}

Suner, Andrea Ortiz ^{[50
,51
]}

Pattison, Natalie ^{[52
,53
]}

Prokopova, Tereza ^{[25
,26
,27
]}

Puntillo, Kathleen ^{[54
]}

Puxty, Kathryn ^{[55
,56
]}

Qahtani, Samah Al ^{[5
,6
]}

Radbruch, Lukas ^{[57
]}

Rodriguez-Ruiz, Emilio ^{[58
,59
,60
]}

Sabar, Ron ^{[61
]}

Schaller, Stefan J. ^{[62
,63
]}

Siddiqui, Shahla ^{[64
]}

Sprung, Charles L. ^{[65
]}

Umbrello, Michele ^{[44
]}

Vergano, Marco ^{[66
]}

机构：

[1] Univ Utrecht, Univ Med Ctr Utrecht, Dept Intens Care Med, Utrecht, Netherlands

[2] Charles Univ Prague, Fac Med 1, Dept Palliat Med, Prague, Czech Republic

[3] Gen Univ Hosp Prague, Prague, Czech Republic

[4] Sapienza Univ Rome, AOU Sant Andrea, Rome, Italy

[5] King Saud Bin Abdulaziz Univ Hlth Sci, Intens Care Dept, Minist Natl Guard Hlth Affairs, Riyadh, Saudi Arabia

[6] Minist Natl Guard Hlth Affairs, King Abdullah Int Med Res Ctr, Riyadh, Saudi Arabia

[7] Hebrew Univ Jerusalem, Fac Med, Sch Nursing, Jerusalem, Israel

[8] Ghent Univ Hosp, Dept Intens Care Med, Ghent, Belgium

[9] Univ Ghent, Fac Med & Hlth Sci, Ghent, Belgium

[10] Royal Devon Univ Healthcare NHS Fdn Trust, Exeter, England

[11] Humanitas Univ, Biomed Sci Dept, Milan, Italy

[12] IRCCS Humanitas Res Hosp, Dept Anaesthesia & Intens Care, Milan, Italy

[13] Duke Univ, Div Pulm & Crit Care Med, Durham, NC 27708 USA

[14] Univ Ottawa, Dept Med, Ottawa, ON, Canada

[15] Bruyere Res Inst, Ottawa, ON, Canada

[16] Univ Birmingham, Sch Nursing & Midwifery, Birmingham, England

[17] Natl Inst Hlth & Care Res, London, England

[18] Univ Udine, Dept Med, Udine, Italy

[19] Gelderse Vallei Hosp, Ede, Netherlands

[20] Med Ctr Leeuwarden, Ctr Intens Care, Leeuwarden, Netherlands

[21] AmsterdamUMC Locat VUmc, Dept Crit Care, Amsterdam, Netherlands

[22] Univ Toronto, Univ Hlth Network, Toronto Western Hosp, Interdept Div Crit Care Med, Toronto, ON, Canada

[23] Univ Hlth Network, Toronto Gen Res Inst, Crit Care & Resp Med, Toronto, ON, Canada

[24] Univ Toronto, Inst Med Sci, Interdept Div Crit Care Med, Toronto, ON, Canada

[25] Masaryk Univ, Univ Hosp Brno, Dept Anaesthesiol & Intens Care Med, Brno, Czech Republic

[26] Masaryk Univ, Fac Med, Brno, Czech Republic

[27] Masaryk Univ, Fac Med, Dept Simulat Med, Brno, Czech Republic

[28] St Louis Hosp, APHP Nord, Intens Care Unit, Famirea Res Grp, Paris, France

[29] Univ Plymouth, Fac Hlth, Sch Nursing & Midwifery, Plymouth, England

[30] Curtin Univ, Curtin Sch Nursing, Perth, Australia

[31] Fudan Univ, Zhongshan Hosp, Dept Nursing, Shanghai, Peoples R China

[32] Masaryk Univ, Univ Hosp Brno, Dept Paediat Anaesthesiol & Intens Care Med, Brno, Czech Republic

[33] Univ Hosp Brno, Dept Anaesthesiol & Intens Care Med 2, Brno, Czech Republic

[34] Univ Naples Federico II, Dept Neurosci Reprod Sci & Dent, Naples, Italy

[35] Univ Hull, Wolfson Palliat Care Res Ctr, Hull York Med Sch, Kingston Upon Hull, England

[36] Natl & Kapodistrian Univ Athens, Med Sch, Evaggelismos Gen Hosp, Dept Intens Care Med 1, Athens, Greece

[37] Charlotte Maxeke Johannesburg Acad Hosp CMJAH, Dept Med, Div Crit Care & Pulmonol, Johannesburg, South Africa

[38] Univ Witwatersrand, Fac Hlth Sci, Johannesburg, South Africa

[39] Kings Coll Hosp NHS Fdn Trust, Dept Crit Care, London, England

[40] Kings Coll London, London, England

[41] Konstanz Hosp, Dept Anesthesiol Crit Care Emergency Med & Pain T, Constance, Germany

[42] Ahmedabad Shaibya Comprehens Care Clin, Ahmadabad, India

[43] Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy

[44] Legnano Gen Hosp, SC Anesthesia & Intens Care, ASST Ovest Milanese, Milan, Italy

[45] Univ Med Ctr Rotterdam, Dept Intens Care Adults, Erasmus MC, Rotterdam, Netherlands

[46] Hosp Sao Jose, Unidade Local Saude Sao Jose, Lisbon, Portugal

[47] Nova Med Sch, Fac Ciencias Med Lisboa, Ctr Clin Academ Lisboa, Lisbon, Portugal

[48] Univ Beira Interior, Fac Ciencias Saude, Covilha, Portugal

[49] Weill Cornell Med Coll, Mem Hosp, New York, NY USA

[50] Hosp Arnau Vilanova Lliria, Valencia, Spain

来源：

INTENSIVE CARE MEDICINE | 2024年 / 50卷 / 12期

关键词：

Intensive care unit; End of life; GRADE; Cultural variations; Decision-making; Palliative care; Communication; Family-centered care; Conflict management; SHARED DECISION-MAKING; FAMILY-MEMBERS EXPERIENCES; CRITICALLY-ILL PATIENTS; BURNOUT SYNDROME; SUSTAINING TREATMENTS; SLEEP QUALITY; ICU PATIENTS; COMMUNICATION STRATEGY; LOVED ONE; PAIN;

D O I：

10.1007/s00134-024-07579-1

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The European Society of Intensive Care Medicine (ESICM) has developed evidence-based recommendations and expert opinions about end-of-life (EoL) and palliative care for critically ill adults to optimize patient-centered care, improving outcomes of relatives, and supporting intensive care unit (ICU) staff in delivering compassionate and effective EoL and palliative care. An international multi-disciplinary panel of clinical experts, a methodologist, and representatives of patients and families examined key domains, including variability across countries, decision-making, palliative-care integration, communication, family-centered care, and conflict management. Eight evidence-based recommendations (6 of low level of evidence and 2 of high level of evidence) and 19 expert opinions were presented. EoL legislation and the importance of respecting the autonomy and preferences of patients were given close attention. Differences in EoL care depending on country income and healthcare provision were considered. Structured EoL decision-making strategies are recommended to improve outcomes of patients and relatives, as well as staff satisfaction and mental health. Early integration of palliative care and the use of standardized tools for symptom assessment are suggested for patients at high risk of dying. Communication training for ICU staff and printed communication aids for families are advocated to improve outcomes and satisfaction. Methods for enhancing family-centeredness of care include structured family conferences and culturally sensitive interventions. Conflict-management protocols and strategies to prevent burnout among healthcare professionals are also considered. The work done to develop these guidelines highlights many areas requiring further research.

引用

页码：2179 / 2181

页数：3

共 171 条

[11] Evidence-Based Palliative Care in the Intensive Care Unit: A Systematic Review of Interventions [J].

Aslakson, Rebecca ;

Cheng, Jennifer ;

Vollenweider, Daniela ;

Galusca, Dragos ;

Smith, Thomas J. ;

Pronovost, Peter J. .

JOURNAL OF PALLIATIVE MEDICINE, 2014, 17 (02) :219-235

[12] Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study [J].

Avidan, Alexander ;

Sprung, Charles L. ;

Schefold, Joerg C. ;

Ricou, Bara ;

Hartog, Christiane S. ;

Nates, Joseph L. ;

Jaschinski, Ulrich ;

Lobo, Suzana M. ;

Joynt, Gavin M. ;

Lesieur, Olivier ;

Weiss, Manfred ;

Antonelli, Massimo ;

Bulow, Hans-Henrik ;

Bocci, Maria G. ;

Robertsen, Annette ;

Anstey, Matthew H. ;

Estebanez-Montiel, Belen ;

Lautrette, Alexandre ;

Gruber, Anastasiia ;

Estella, Angel ;

Mullick, Sudakshina ;

Sreedharan, Roshni ;

Michalsen, Andrej ;

Feldman, Charles ;

Tisljar, Kai ;

Posch, Martin ;

Ovu, Steven ;

Tamowicz, Barbara ;

Demoule, Alexandre ;

Ganz, Freda DeKeyser ;

Pargger, Hans ;

Noto, Alberto ;

Metnitz, Philipp ;

Zubek, Laszlo ;

de la Guardia, Veronica ;

Danbury, Christopher M. ;

Szucs, Orsolya ;

Protti, Alessandro ;

Filipe, Mario ;

Simpson, Steven Q. ;

Green, Cameron ;

Giannini, Alberto M. ;

Soliman, Ivo W. ;

Piras, Claudio ;

Caser, Eliana B. ;

Hache-Marliere, Manuel ;

Mentzelopoulos, Spyros .

LANCET RESPIRATORY MEDICINE, 2021, 9 (10) :1101-1110

[13] Survey of End-of-Life Care in Intensive Care Units in Ain Shams University Hospitals, Cairo, Egypt [J].

Azab, Sonya M. S. ;

Abdul-Rahman, Samia A. ;

Esmat, Ibrahim M. .

HEC FORUM, 2022, 34 (01) :25-39

[14] Meeting the needs of intensive care unit patient families - A multicenter study [J].

Azoulay, E ;

Pochard, F ;

Chevret, S ;

Lemaire, F ;

Mokhtari, M ;

Le Gall, JR ;

Dhainaut, JF ;

Schlemmer, B .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (01) :135-139

[15] Half the families of intensive care unit patients experience inadequate communication with physicians [J].

Azoulay, E ;

Chevret, S ;

Leleu, G ;

Pochard, F ;

Barboteu, M ;

Adrie, C ;

Canoui, P ;

Le Gall, JR ;

Schlemmer, B .

CRITICAL CARE MEDICINE, 2000, 28 (08) :3044-3049

[16] Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients - A multicenter, prospective, randomized, controlled trial [J].

Azoulay, E ;

Pochard, F ;

Chevret, S ;

Jourdain, M ;

Bornstain, C ;

Wernet, A ;

Cattaneo, I ;

Annane, D ;

Brun, F ;

Bollaert, PE ;

Zahar, JR ;

Goldgran-Toledano, D ;

Adrie, C ;

Joly, LM ;

Tayoro, J ;

Desmettre, T ;

Pigne, E ;

Parrot, A ;

Sanchez, O ;

Poisson, C ;

Le Gall, JR ;

Schlemmer, B ;

Lemaire, F .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (04) :438-442

[17] Symptoms of Mental Health Disorders in Critical Care Physicians Facing the Second COVID-19 Wave A Cross-Sectional Study [J].

Azoulay, Elie ;

Pochard, Frederic ;

Reignier, Jean ;

Argaud, Laurent ;

Bruneel, Fabrice ;

Courbon, Pascale ;

Cariou, Alain ;

Klouche, Kada ;

Labbe, Vincent ;

Barbier, Francois ;

Guitton, Christophe ;

Demoule, Alexandre ;

Kouatchet, Achille ;

Guisset, Olivier ;

Jourdain, Merce ;

Papazian, Laurent ;

Van der Meersch, Guillaume ;

Reuter, Danielle ;

Souppart, Virginie ;

Resche-Rigon, Matthieu ;

Darmon, Michael ;

Kentish-Barnes, Nancy .

CHEST, 2021, 160 (03) :944-955

[18] Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak [J].

Azoulay, Elie ;

De Waele, Jan ;

Ferrer, Ricard ;

Staudinger, Thomas ;

Borkowska, Marta ;

Povoa, Pedro ;

Iliopoulou, Katerina ;

Artigas, Antonio ;

Schaller, Stefan J. ;

Hari, Manu Shankar ;

Pellegrini, Mariangela ;

Darmon, Michael ;

Kesecioglu, Jozef ;

Cecconi, Maurizio .

ANNALS OF INTENSIVE CARE, 2020, 10 (01)

[19] Questions to improve family-staff communication in the ICU: a randomized controlled trial [J].

Azoulay, Elie ;

Forel, Jean-Marie ;

Vinatier, Isabelle ;

Truillet, Romain ;

Renault, Anne ;

Valade, Sandrine ;

Jaber, Samir ;

Durand-Gasselin, Jacques ;

Schwebel, Carole ;

Georges, Hughes ;

Merceron, Sybille ;

Cariou, Alain ;

Moussa, Myriam ;

Hraiech, Sami ;

Argaud, Laurent ;

Leone, Marc ;

Curtis, J. Randall ;

Kentish-Barnes, Nancy ;

Jouve, Elisabeth ;

Papazian, Laurent .

INTENSIVE CARE MEDICINE, 2018, 44 (11) :1879-1887

[20] Prevalence and Factors of Intensive Care Unit Conflicts The Conflicus Study [J].

Azoulay, Elie ;

Timsit, Jean-Francois ;

Sprung, Charles L. ;

Soares, Marcio ;

Rusinova, Katerina ;

Lafabrie, Ariane ;

Abizanda, Ricardo ;

Svantesson, Mia ;

Rubulotta, Francesca ;

Ricou, Bara ;

Benoit, Dominique ;

Heyland, Daren ;

Joynt, Gavin ;

Francais, Adrien ;

Azeivedo-Maia, Paulo ;

Owczuk, Radoslaw ;

Benbenishty, Julie ;

de Vita, Michael ;

Valentin, Andreas ;

Ksomos, Akos ;

Cohen, Simon ;

Kompan, Lidija ;

Ho, Kwok ;

Abroug, Fekri ;

Kaarlola, Anne ;

Gerlach, Herwig ;

Kyprianou, Theodoros ;

Michalsen, Andrej ;

Chevret, Sylvie ;

Schlemmer, Benoit .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 180 (09) :853-860

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