Metabolic dysfunction-associated steatotic liver disease and cardiovascular risk: a comprehensive review

被引：25

作者：

Zheng, Haixiang ^{[1
,4
]}

Sechi, Leonardo Antonio ^{[1
,5
]}

Navarese, Eliano Pio ^{[3
]}

Casu, Gavino ^{[3
]}

Vidili, Gianpaolo ^{[2
]}

机构：

[1] Univ Sassari, Dept Biomed Sci, I-07100 Sassari, Italy

[2] Univ Sassari, Dept Med Surg & Pharm, I-07100 Sassari, Italy

[3] Univ Sassari, Clin & Expt Cardiol, Clin & Intervent Cardiol, Sassari, Italy

[4] Shantou Univ, Dept Cardiol, Affiliated Hosp 2, Med Coll, Shantou 515041, Peoples R China

[5] AOU Sassari, Complex Struct Microbiol & Virol, I-07100 Sassari, Italy

来源：

CARDIOVASCULAR DIABETOLOGY | 2024年 / 23卷 / 01期

关键词：

Metabolic dysfunction-associated steatotic liver disease; Nonalcoholic fatty liver disease; Metabolic-associated fatty liver disease; Cardiovascular risk; MAGNETIC-RESONANCE ELASTOGRAPHY; NONALCOHOLIC STEATOHEPATITIS; TRANSIENT ELASTOGRAPHY; INSULIN-RESISTANCE; FIBROSIS; VARIANT; HEART; MAFLD; NAFLD; GENE;

D O I：

10.1186/s12933-024-02434-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed nonalcoholic fatty liver disease (NAFLD), poses a significant global health challenge due to its increasing prevalence and strong association with cardiovascular disease (CVD). This comprehensive review summarizes the current knowledge on the MASLD-CVD relationship, compares analysis of how different terminologies for fatty liver disease affect cardiovascular (CV) risk assessment using different diagnostic criteria, explores the pathophysiological mechanisms connecting MASLD to CVD, the influence of MASLD on traditional CV risk factors, the role of noninvasive imaging techniques and biomarkers in the assessment of CV risk in patients with MASLD, and the implications for clinical management and prevention strategies. By incorporating current research and clinical guidelines, this review provides a comprehensive overview of the complex interplay between MASLD and cardiovascular health.

引用

页数：20

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