Two New Phloroglucinol Derivatives from Syzygium austroyunnanense

被引：0

作者：

Xu, Shao-Hua ^{[1
]}

Xu, Wen ^{[1
]}

He, Yuan-Biao ^{[1
]}

Zhao, Yong ^{[1
]}

机构：

[1] Yunnan Normal Univ, Fac Chem & Chem Engn, Juxian St, Kunming 650500, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2024年 / 60卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Myrtaceae; Syzygium austroyunnanense; phloroglucinols; alpha-glucosidase;

D O I：

10.1007/s10600-024-04512-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Our continuous phytochemical investigation of the twigs and leaves of Syzygium austroyunnanense has led to the isolation of two new phloroglucinol derivatives, austroyunone F (1) and austroyunone G (2). Their structures were determined via extensive spectroscopic data including NMR along with HR-ESI-MS. Compound 1 showed significant inhibitory activity with an IC50 value of 2.64 mu M against alpha-glucosidase.

引用

页码：1029 / 1032

页数：4

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