Toll-like receptor response to Zika virus infection: progress toward infection control

被引：2

作者：

Mohammad Enamul Hoque Kayesh ^{[1
]}

Michinori Kohara ^{[2
]}

Kyoko Tsukiyama-Kohara ^{[3
]}

机构：

[1] Patuakhali Science and Technology University,Department of Microbiology and Public Health, Faculty of Animal Science and Veterinary Medicine

[2] Tokyo Metropolitan Institute of Medical Science,Department of Microbiology and Cell Biology

[3] Kagoshima University,Transboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine

来源：

npj Viruses | / 3卷 / 1期

关键词：

D O I：

10.1038/s44298-025-00102-3

中图分类号：

学科分类号：

摘要：

Infection with the Zika virus (ZIKV) poses a threat to human health. An improved understanding of the host Toll-like receptor response, disease onset, and viral clearance in vivo and in vitro may lead to the development of therapeutic or prophylactic interventions against viral infections. Currently, no clinically approved ZIKV vaccine is available, highlighting the need for its development. In this study, we discuss the progress in the Zika vaccine, including advances in the use of Toll-like receptor agonists as vaccine adjuvants to enhance vaccine efficacy.

引用