Solvent Controlled Chemodivergent Sulfonyl Addition into Enynones: Synthesis of α-Furyl Sulfones and Stereodefined Vinyl Sulfones

被引：0
作者：
Mercy, A. Antony Haritha
Priya, V. R. Padma [1 ]
Natarajan, K. [1 ]
Kataria, Ramesh [2 ,3 ]
Nandi, Ganesh Chandra [1 ]
机构：
[1] Natl Inst Technol, Dept Chem, Tiruchirappalli 620015, Tamilnadu, India
[2] Panjab Univ, Dept Chem, Chandigarh 160014, India
[3] Panjab Univ, Ctr Adv Studies Chem, Chandigarh 160014, India
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 90卷 / 01期
关键词：
DISCOVERY; INHIBITORS; CATALYST;
D O I：
10.1021/acs.joc.4c02165
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Sodium salt of aryl sulfinic acid reacts with enynone in a different manner, yielding alpha-furyl sulfone and stereodefined vinyl sulfone in toluene and EtOH respectively in the presence of ZnCl2. The salient features of this protocol include chemoselectivity, broad substrate scope, high efficiency, high yield, and easy purification. The synthetic utilities of the products are demonstrated by cycloaddition and cis-trans photoisomerization reactions.
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页码：830 / 839
页数：10
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