共 24 条
A privacy-preserving dependable deep federated learning model for identifying new infections from genome sequences
被引:0
|作者:
Mehedi, Sk. Tanzir
[1
]
Abdulrazak, Lway Faisal
[2
,3
]
Ahmed, Kawsar
[4
,5
,6
]
Uddin, Muhammad Shahin
[1
]
Bui, Francis M.
[4
]
Chen, Li
[4
]
Moni, Mohammad Ali
[7
,8
]
Al-Zahrani, Fahad Ahmed
[9
]
机构:
[1] Mawlana Bhashani Sci & Technol Univ, Dept Informat & Commun Technol, Santosh 1902, Tangail, Bangladesh
[2] Middle Tech Univ, Elect Engn Tech Coll, Baghdad, Iraq
[3] Cihan Univ Sulaimaniya, Dept Comp Sci, Sulaimaniya 46001, Kurdistan Regio, Iraq
[4] Univ Saskatchewan, Dept Elect & Comp Engn, 57 Campus Dr, Saskatoon, SK S7N 5A9, Canada
[5] Daffodil Int Univ, Dept Comp Sci & Engn, Hlth Informat Res Lab, Dhaka 1216, Bangladesh
[6] Mawlana Bhashani Sci & Technol Univ, Grp Biophotomati Informat & Commun Technol, Santosh 1902, Tangail, Bangladesh
[7] Charles Sturt Univ, Artificial Intelligence & Cyber Future Inst, AI & Digital Hlth Technol, Bathurst, NSW 2795, Australia
[8] Charles Sturt Univ, Rural Hlth Res Inst, AI & Digital Hlth Technol, Orange, NSW 2800, Australia
[9] Umm Al Qura Univ, Dept Comp Engn, Mecca 24381, Saudi Arabia
来源:
SCIENTIFIC REPORTS
|
2025年
/
15卷
/
01期
关键词:
Deep federated learning;
Privacy and security;
Dependability;
Coronavirus;
Genome sequence;
NEURAL-NETWORKS;
D O I:
10.1038/s41598-025-89612-x
中图分类号:
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
The traditional molecular-based identification (TMID) technique of new infections from genome sequences (GSs) has made significant contributions so far. However, due to the sensitive nature of the medical data, the TMID technique of transferring the patient's data to the central machine or server may create severe privacy and security issues. In recent years, the progression of deep federated learning (DFL) and its remarkable success in many domains has guided as a potential solution in this field. Therefore, we proposed a dependable and privacy-preserving DFL-based identification model of new infections from GSs. The unique contributions include automatic effective feature selection, which is best suited for identifying new infections, designing a dependable and privacy-preserving DFL-based LeNet model, and evaluating real-world data. To this end, a comprehensive experimental performance evaluation has been conducted. Our proposed model has an overall accuracy of 99.12% after independently and identically distributing the dataset among six clients. Moreover, the proposed model has a precision of 98.23%, recall of 98.04%, f1-score of 96.24%, Cohen's kappa of 83.94%, and ROC AUC of 98.24% for the same configuration, which is a noticeable improvement when compared to the other benchmark models. The proposed dependable model, along with empirical results, is encouraging enough to recognize as an alternative for identifying new infections from other virus strains by ensuring proper privacy and security of patients' data.
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页数:24
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