Mediterranean diet and osteoarthritis: an update

被引:1
|
作者
Veronese, Nicola [1 ]
Ragusa, Francesco Saverio [1 ]
Dominguez, Ligia J. [2 ]
Cusumano, Claudia [1 ]
Barbagallo, Mario [1 ]
机构
[1] Univ Palermo, Dept Hlth Promot Mother & Child Care, Internal Med & Med Specialties, Palermo, Italy
[2] Kore Univ Enna, Dept Med & Surg, Piazza Univ, I-94100 Enna, Italy
关键词
Mediterranean diet; Osteoarthritis; Inflammation; Oxidative stress; Pain; Older adults; METABOLIC SYNDROME; INFLAMMATORY DISEASE; OBESITY; CONSUMPTION; PREVALENCE; INCREASES; BURDEN; HEALTH; ROLES;
D O I
10.1007/s40520-024-02883-8
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
The Mediterranean diet has gained significant attention for its potential health benefits on diverse pathological conditions including osteoarthritis (OA), a prevalent degenerative joint disease characterized by cartilage breakdown and inflammation. Numerous observational studies have suggested that adherence to the Mediterranean diet, may have protective effects against OA. The abundance of antioxidants and anti-inflammatory compounds and omega-3 fatty acids, among the Mediterranean diet components is believed to contribute to its beneficial effects on OA. Research investigating the association between the Mediterranean diet and OA has shown promising results. Several observational studies have reported that adherence to the Mediterranean diet is associated with a reduced risk of developing OA and with lower severity of OA symptoms. Additionally, intervention studies have demonstrated improvements in pain, function, and quality of life among OA patients following a Mediterranean diet intervention. Furthermore, emerging evidence suggests potential mechanisms underlying the protective effects of the Mediterranean diet against OA, including its ability to reduce inflammation, oxidative stress, and cartilage degradation. However, further well-designed randomized controlled trials and mechanistic studies are needed to elucidate the precise mechanisms and establish causality. In conclusion, the Mediterranean diet appears to be a promising dietary approach for the prevention and management of OA. Its rich array of nutrients and bioactive compounds may exert protective effects against OA development and progression, although more research is warranted to confirm these findings and elucidate underlying mechanisms.
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页数:10
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