Green and Efficient Synthesis of Pyrazole-Conjugated Chromene Derivatives

被引:0
|
作者
Chary, N. Ganapathi [1 ,2 ]
Gutta, Madhusudhan [1 ]
Vidya, K. [2 ]
机构
[1] MSN R&D Dept, R&D Dept, Hyderabad 502307, Telangana, India
[2] JNTU H Coll Engn, Dept Chem, Karimnagar 505501, Telangana, India
关键词
pyrazoles; chromenes; green chemistry; L-proline; one-pot reaction; IN-VITRO; 4-ARYL-4H-CHROMENES; IDENTIFICATION; DISCOVERY;
D O I
10.1134/S1070428024090148
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pyrazolyl-substituted chromene analogues have been synthesized in one pot from 1H-pyrazole-5-carbaldehydes, malononitrile, and cyclohexane-1,3-dione or dimedone in the presence of L-proline as catalyst using ethanol as solvent under reflux conditions for 2-3 h. This approach offers notable advantages such as high yields, environmental friendliness, easy experimental procedure, short reaction time, and mild reaction conditions.
引用
收藏
页码:1720 / 1724
页数:5
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