Green and Efficient Synthesis of Pyrazole-Conjugated Chromene Derivatives

被引：0

作者：

Chary, N. Ganapathi ^{[1
,2
]}

Gutta, Madhusudhan ^{[1
]}

Vidya, K. ^{[2
]}

机构：

[1] MSN R&D Dept, R&D Dept, Hyderabad 502307, Telangana, India

[2] JNTU H Coll Engn, Dept Chem, Karimnagar 505501, Telangana, India

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 60卷 / 09期

关键词：

pyrazoles; chromenes; green chemistry; L-proline; one-pot reaction; IN-VITRO; 4-ARYL-4H-CHROMENES; IDENTIFICATION; DISCOVERY;

D O I：

10.1134/S1070428024090148

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrazolyl-substituted chromene analogues have been synthesized in one pot from 1H-pyrazole-5-carbaldehydes, malononitrile, and cyclohexane-1,3-dione or dimedone in the presence of L-proline as catalyst using ethanol as solvent under reflux conditions for 2-3 h. This approach offers notable advantages such as high yields, environmental friendliness, easy experimental procedure, short reaction time, and mild reaction conditions.

引用

页码：1720 / 1724

页数：5

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