Unveiling the therapeutic potential of insect-derived natural products for drug discovery

被引：1

作者：

Anal, Jasha Momo H. ^{[1
,2
]}

Mozhui, Lobeno ^{[3
]}

Rokhum, Samuel Lalthazuala ^{[4
]}

机构：

[1] CSIR, Indian Inst Integrat Med, Nat Prod & Med Chem Div, Jammu 180001, India

[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India

[3] Nagaland Univ, Dept Zool, Ecol & Entomol Lab, Lumami 798627, India

[4] Natl Inst Technol Silchar, Dept Chem, Silchar, India

来源：

FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES | 2025年 / 11卷 / 01期

关键词：

Biologically-active compounds; Entomotherapy; Drug discovery; Human health; Sustainability; PERIPLANETA-AMERICANA EXTRACT; IMPORTED FIRE ANTS; EDIBLE INSECTS; ANTIMICROBIAL PEPTIDE; CANTHARIDIN ANALOGS; IN-VITRO; VENOM; IDENTIFICATION; CHEMISTRY; CONSTITUENTS;

D O I：

10.1186/s43094-024-00758-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

BackgroundThe recent FDA-approved Ycanth (cantharidin) for treating Molluscum contagiosum, a viral skin infection, was first reported from blister beetles. Medicinal insects are reservoirs for exploring bioactive molecules, which have various benefits. Their use in traditional medicinal practices explains why uncovering new chemical substances is worthwhile.Main body of the abstractInsect-derived natural products with diverse and unique structures are significant for drug discovery and development potential. Various natural products are reported from insect sources; in this context, it also emphasizes the importance of active global participation among researchers, as it offers significant potential for developing a sustainable approach to why this should not remain untouched for ever-increasing unmet challenges.ConclusionHence, practitioners in natural product chemistry and allied disciplines have a role in understating the enormous potential of discovering bioactive metabolites for their medicinal value to human health.

引用

页数：12

共 87 条

[51] The chemistry of snake venom and its medicinal potential [J].