Human umbilical cord mesenchymal stem cell-derived extracellular vesicles harboring IGF-1 improve ovarian function of mice with premature ovarian insufficiency through the Nrf2/HO-1 pathway

被引:0
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作者
Hui Miao [1 ]
Congxiu Miao [2 ]
Na Li [3 ]
Jing Han [4 ]
机构
[1] Heping Hospital of Changzhi Medical College,Department of Reproductive Genetics
[2] Institute of Reproduction and Genetics of Changzhi Medical College,undefined
[3] Key Laboratory of Reproduction and Genetics of Changzhi Medical College,undefined
[4] Key Laboratory of Reproduction Engineer of Shanxi Health Committee,undefined
关键词
Human umbilical cord mesenchymal stem cells; Extracellular vesicles; Premature ovarian insufficiency; IGF-1; Nrf2/HO-1; Granulosa cell autophagy; Ovarian function;
D O I
10.1186/s13048-024-01536-8
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