CAR T-Cell Therapy: A Promising Modality for Autoimmune Diseases

被引：0

作者：

Thakral, Deepshi ^{[1
]}

Ramanan, Tejas ^{[2
]}

Bagri, Narendra Kumar ^{[3
]}

机构：

[1] Dr BRAICH All India Inst Med Sci, Lab Oncol Unit, New Delhi, India

[2] Univ Birmingham, Birmingham, England

[3] All India Inst Med Sci AIIMS, Dept Pediat, Div Pediat Rheumatol, New Delhi 110029, India

来源：

INDIAN PEDIATRICS | 2024年 / 61卷 / 10期

关键词：

Chimeric antigen receptor; Chimeric autoantibody receptor (CAAR) T-cells; Refractory; Systemic lupus erythematosus; CANCER;

D O I：

10.1007/s13312-024-3300-3

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Chimeric Antigen Receptor (CAR) T-cells have emerged as a promising immune effector cell-based therapy. With promising results and approval for the treatment of hematological malignancies, we discuss the scope of this novel therapeutic modality in systemic autoimmune diseases and immune-mediated inflammatory disorders refractory to conventional and biological disease-modifying agents.

引用

页码：987 / 991

页数：5

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