Pericardiotomy as a novel treatment for heart failure with preserved ejection fraction

被引：0

作者：

Doi, Shunichi ^{[1
]}

Borlaug, Barry A. ^{[1
,2
]}

机构：

[1] Mayo Clin, Dept Cardiovasc Dis, Rochester, MN 55905 USA

[2] Mayo Clin & Mayo Fdn, 200 First St SW, Rochester, MN 55905 USA

来源：

HEART FAILURE REVIEWS | 2025年 / 30卷 / 01期

关键词：

Pericardiotomy; Heart failure with preserved ejection fraction; Pericardium; Catheter intervention; VENTRICULAR DIASTOLIC PRESSURE; BIAXIAL MECHANICAL-PROPERTIES; TRICUSPID REGURGITATION; HYPERTENSION; DYSFUNCTION; OVERLOAD; EXERCISE; RESERVE; OUTPUT;

D O I：

10.1007/s10741-024-10451-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The pericardium plays an important role in modulating cardiac performance and hemodynamics in patients with heart failure with preserved ejection fraction (HFpEF). Pericardial constraint increases filling pressures in patients with HFpEF, particularly those with the obesity phenotype, atrial myopathy, right ventricular dysfunction, and tricuspid regurgitation. Preclinical and early stage clinical studies indicate that pericardiotomy may become a novel treatment for HFpEF. This review summarizes and discusses the pathophysiology of pericardial restraint and the possibility of pericardiotomy in HFpEF.

引用

页码：137 / 142

页数：6

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