The Role of Artificial Intelligence and Machine Learning in Accelerating the Discovery and Development of Nanomedicine

被引:1
|
作者
Agrahari, Vivek [1 ]
Choonara, Yahya E. [2 ,3 ]
Mosharraf, Mitra [4 ,5 ]
Patel, Sravan Kumar [6 ,7 ]
Zhang, Fan [8 ,9 ,10 ]
机构
[1] Old Dominion Univ, Eastern Virginia Med Sch, CONRAD, Norfolk, VA 23507 USA
[2] Univ Witwatersrand, Sch Therapeut Sci, Wits Adv Drug Delivery Platform Res Unit, Fac Hlth Sci,Dept Pharm & Pharmacol, Johannesburg, South Africa
[3] Univ Witwatersrand, Wits Infect Dis & Oncol Res Inst, Fac Hlth Sci, Johannesburg, South Africa
[4] HTD Biosyst, 3197 Independence Dr, Livermore, CA 94551 USA
[5] Engimata, 3197 Independence Dr, Livermore, CA 94551 USA
[6] Univ Pittsburgh, Sch Pharm, Dept Pharmaceut Sci, Pittsburgh, PA 15213 USA
[7] Magee Womens Res Inst, Pittsburgh, PA 15213 USA
[8] Univ Florida, Coll Pharm, Dept Pharmaceut Sci, 1350 Ctr Dr, Gainesville, FL 32610 USA
[9] Univ Florida, Coll Med, Dept Pharmacol & Therapeut, 1200 Newell Dr, Gainesville, FL 32610 USA
[10] Univ Florida, Coll Engn, Dept Chem Engn, 1006 Ctr Dr, Gainesville, FL 32611 USA
基金
美国国家卫生研究院;
关键词
artificial intelligence; machine learning; nanomedicine; nanoparticle; nanotechnology;
D O I
10.1007/s11095-024-03798-9
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The unique potential of nanomedicine to address challenging health issues is rapidly advancing the field, leading to the generation of more effective products. However, these complex systems often pose several challenges with respect to their design for specific functionality, scalable manufacturing, characterization, quality control, and clinical translation. In this regard, the application of artificial intelligence (AI) and machine learning (ML) approaches can enable faster and more accurate data assessment, identifying trends and predicting outcomes, leading to efficient nanomedicine product development. This perspective paper discusses the potential of AI and ML in nanomedicine product development with a focus on their applications in discovery, assessment, manufacturing, and clinical trials. The potential limitations of AI and ML approaches in nanomedicine product development are also covered.
引用
收藏
页码:2289 / 2297
页数:9
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