Impact of aneurysm sac size on the effectiveness of endovascular coiling in patient-specific middle cerebral artery aneurysms: a computational study

被引:0
作者
Yao, Zhichao [1 ]
Wen, Hao [2 ]
机构
[1] Wenzhou Med Univ, Affiliated Hosp 2, Dept Gen Surg, Yuying Childrens Hosp, Wenzhou 325024, Peoples R China
[2] Wenzhou Med Univ, Affiliated Hosp 2, Dept Emergency, Yuying Childrens Hosp, Wenzhou 325024, Peoples R China
来源
SCIENTIFIC REPORTS | 2025年 / 15卷 / 01期
关键词
MCA aneurysms; Endovascular coiling; CFD; Hemodynamic efficiency; WSS; FLOW;
D O I
10.1038/s41598-025-92298-w
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This study investigates the hemodynamic efficiency of endovascular coiling in the treatment of patient-specific middle cerebral artery (MCA) aneurysms using computational models of both original and scaled-down geometries. Computational fluid dynamic (CFD) is used for the blood flow modelling inside cerebral aneurysms. The Casson non-Newtonian model is employed to simulate blood flow dynamics, while a porous condition represents the coiling within the aneurysm sac. Key hemodynamic factors, including wall shear stress (WSS) and oscillatory shear index (OSI), are analyzed to evaluate the effectiveness of coiling across different aneurysm sizes. Results indicate that coiling significantly reduces rupture risk, with larger sac volumes demonstrating a more pronounced decrease in high-risk hemodynamic zones. These findings offer insights into optimizing endovascular treatments for varying aneurysm morphologies.
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页数:8
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