Exploring the green synthesis of silver nanoparticles using natural extracts and their potential for cancer treatment

被引:10
作者
Abdellatif, Ahmed A. H. [1 ]
Mostafa, Mahmoud A. H. [2 ,3 ]
Konno, Hiroyuki [4 ]
Younis, Mahmoud A. [5 ]
机构
[1] Qassim Univ, Coll Pharm, Dept Pharmaceut, Buraydah 51452, Al Qassim, Saudi Arabia
[2] Taibah Univ, Coll Pharm, Dept Pharmacognosy & Pharmaceut Chem, Al Madinah 41477, Saudi Arabia
[3] Al Azhar Univ, Fac Pharm, Departmentof Pharmacognosy, Assiut 71524, Egypt
[4] Yamagata Univ, Dept Chem & Biol Engn, Yonezawa, Yamagata 9828510, Japan
[5] Assiut Univ, Fac Pharm, Dept Ind Pharm, Assiut 71526, Egypt
关键词
Silver nanoparticles (AgNPs); Green synthesis; Natural extracts; Sustainability; Cancer therapy; NECROSIS-FACTOR-ALPHA; GOLD NANOPARTICLES; CELL-LINE; QUANTUM DOTS; ANTICANCER ACTIVITY; ANTITUMOR-ACTIVITY; AQUEOUS EXTRACT; PLANT-EXTRACTS; DRUG-DELIVERY; LEAF EXTRACT;
D O I
10.1007/s13205-024-04118-z
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Silver nanoparticles (AgNPs) have attracted increasing attention in nanomedicine, with versatile applications in drug delivery, antimicrobial treatments, and cancer therapies. While chemical synthesis remains a common approach for AgNP production, ensuring environmental sustainability requires a shift toward eco-friendly, "green" synthesis techniques. This article underscores the promising role of plant extracts in the green synthesis of AgNPs, highlighting the importance of their natural sources and diverse bioactive compounds. Various characterization methods for these nanomaterials are also reviewed. Furthermore, the anticancer potential of green AgNPs (Gr-AgNPs) is examined, focusing on their mechanisms of action and the challenges to their clinical implementation. Finally, future directions in the field are discussed.
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页数:21
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