Assume that A, B and C are three linear relations on certain linear spaces. The main objective of this note is to present some necessary and sufficient conditions for the existence of the solutions X of the operator equation A=BXC\documentclass[12pt]{minimal}
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\begin{document}$$A = BXC$$\end{document}. The obtained characterizations extend and complete some known operator factorization results due to R.G. Douglas, Z. Sebestyén and D. Popovici.