Synthesis and Transformations of Novel Shiff Bases Derived from 1-[2-Methyl-4-(methylsulfanyl)quinolin-3-yl]propan-2-ones

被引:0
作者
Aleksanyan, I. L. [1 ]
Hambardzumyan, L. P. [1 ]
机构
[1] Yerevan State Univ, Yerevan 375025, Armenia
关键词
quinoline; methyl iodide; Schiff bases; (methylsulfanyl)quinoline; (chloroallyl)quinoline; sulfanyl-quinoline; quinolinylpropanones; sulfate hydrolysis; green chemistry; CANCER AGENTS; DERIVATIVES; QUINOLINE;
D O I
10.1134/S1070428024080025
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel Schiff base derivatives were synthesized, starting from 1-[2-methyl-4-sulfanylquinolin-3-yl]-propan-2-ones and 1-[2-methyl-4-(methylsulfanyl)quinoline, substituted in the benzene ring. To obtain the Schiff base derivatives containing the 4-(methylsulfanyl) group, the corresponding 4-sulfanylquinoline-propan-2-ones and 3-(2-chloroallyl)-4-sulfanylquinolines were methylated, and then the chloroallyl group in the resulting 3-(2-chloroallyl)-4-(methylsulfanyl)quinolines was subjected to acid hydrolysis.
引用
收藏
页码:1585 / 1590
页数:6
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