Preparation of polypyrrole/chitosan-sodium alginate composite microspheres and their slow-release properties

被引：0

作者：

Li, Sha ^{[1
,2
]}

Zhang, Xinhao ^{[1
,2
]}

Jia, Rui ^{[1
,2
,3
]}

Luo, Yu ^{[1
,2
,3
]}

Xing, Jianyu ^{[1
,2
,3
]}

机构：

[1] School of Water and Environment, Chang'an University, Xi'an

[2] Key Laboratory of Subsurface Hydrology and Ecological Effect in Arid Region, The Ministry of Education, Chang'an University, Xi'an

[3] Key Laboratory of Eco-Hydrology and Water Security in Arid and Semi-Arid Regions, Ministry of Water Resources, Chang'an University, Xi'an

来源：

Fuhe Cailiao Xuebao/Acta Materiae Compositae Sinica | 2024年 / 41卷 / 07期

关键词：

composite gel microspheres; drug release; indolebutyric acid; photothermal effect; polypyrrole;

D O I：

10.13801/j.cnki.fhclxb.20231123.001

中图分类号：

学科分类号：

摘要：

The development of novel drug controlled release composite materials is of great significance in the fields of medicine and agriculture. Using chitosan and sodium alginate (CS-Alg) gel network as carrier, PPy/CS-Alg composite slow-release material was prepared by in-situ oxidation of polypyrrole (PPy). The microstructure, structure composition and photothermal conversion properties were studied by SEM, FTIR, XPS and UV-vis-NIR. Indolebutyric acid (IBA) was used as a model drug molecule to study its sustained release performance. The results show that the porous morphology of PPy/CS-Alg microspheres is conducive to the loading and release of IBA. The PPy oxidized state formed by in-situ oxidation can be slowly reduced in the CS-Alg gel network, and changes from a positive state to an uncharged state. As a result, IBA can be slowly released from the gel network of PPy/CS-Alg microspheres, with the long-term release rate of 56.12%. In addition, the temperature of PPy/CS-Alg microspheres under simulated sunlight can rise from 26℃ to 39℃ based on the photothermal effect of PPy, which is conducive to the formation of temperature gradients inside and outside the microspheres and further enhancing the slow-release of IBA. The controlled release material of auxin IBA based on the slow reduction and photothermal effect of PPy has broad application prospects in the agricultural field. © 2024 Beijing University of Aeronautics and Astronautics (BUAA). All rights reserved.

引用

页码：3757 / 3764

页数：7

共 25 条

[1]

DUDLEY N, ALEXANDER S., Agriculture and biodiversity: A review, Biodiversity, 18, 2-3, pp. 45-49, (2017)

[2]

ZHAO M, ZHOU H, CHEN L, Et al., Carboxymethyl chitosan grafted trisiloxane surfactant nanoparticles with pH sensitivity for sustained release of pesticide, Carbohydrate Polymers, 243, (2020)

[3]

XU X, BAI B, WANG H, Et al., A near-infrared and temperature-responsive pesticide release platform through core-shell polydopamine@PNIPAm nanocomposites, ACS Applied Materials & Interfaces, 9, 7, pp. 6424-6432, (2017)

[4]

ABDULLAH T, OKAY O., 4D printing of body temperature-responsive hydrogels based on poly(acrylic acid) with shape-memory and self-healing abilities, ACS Applied Bio Materials, 6, 2, pp. 703-711, (2023)

[5]

GAO C, HUANG Q X, LAN Q P, Et al., A user-friendly herbicide derived from photo-responsive supramolecular vesicles, Nature Communications, 9, (2018)

[6]

CUI J, HUANG J, YAN Y, Et al., Ferroferric oxide loaded near-infrared triggered photothermal microneedle patch for controlled drug release, Journal of Colloid and Interface Science, 617, pp. 718-729, (2022)

[7]

YANG Y B, WU J R, BREMNER D H, Et al., A multifunctional nanoplatform based on MoS<sub>2</sub>-nanosheets for targeted drug delivery and chemo-photothermal therapy, Colloids and Surfaces B: Biointerfaces, 185, (2020)

[8]

ARAFA E G, SABAA M W, MOHAMED R R, Et al., Preparation of biodegradable sodium alginate/carboxymethylchitosan hydrogels for the slow-release of urea fertilizer and their antimicrobial activity, Reactive & Functional Polymers, 174, (2022)

[9]

KESHVARDOOSTCHOKAMI M, MAJIDI M, ZAMAMANI A, Et al., A review on the use of chitosan and chitosan derivatives as the bio-adsorbents for the water treatment: Removal of nitrogen-containing pollutants, Carbohydrate Polymers, 273, (2021)

[10]

VAKILI M, RAFATULLAH M, SALAMATINIA B, Et al., Application of chitosan and its derivatives as adsorbents for dye removal from water and wastewater: A review, Carbohydrate Polymers, 113, pp. 115-130, (2014)

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