A Portal to Highly Valuable Pyridonyl Vinyl Sulfonyl Fluorides and Aliphatic Sulfonyl Fluorides

被引：0

作者：

Zeng, Shi-Qi

Fayad, Eman ^{[2
]}

Abu Ali, Ola A. ^{[3
]}

Sun, Bing ^{[1
]}

Qin, Hua-Li ^{[1
]}

机构：

[1] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, Wuhan 430070, Peoples R China

[2] Taif Univ, Coll Sci, Dept Biotechnol, POB 11099, Taif 21944, Saudi Arabia

[3] Taif Univ, Coll Sci, Dept Chem, Taif 21944, Saudi Arabia

来源：

SYNTHESIS-STUTTGART | 2025年 / 57卷 / 04期

基金：

中国国家自然科学基金;

关键词：

2-pyridones; pyridonyl vinyl sulfonyl fluorides; Michael addition; pyridonyl aliphatic sulfonyl fluorides; click chemistry; 2-PYRIDONES; IDENTIFICATION; SUBSTITUTION; ALKYLATION; INHIBITORS; DISCOVERY; SUFEX;

D O I：

10.1055/s-0043-1773500

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient method for selective Michael addition of 2-pyridones to ethenesulfonyl fluoride (ESF) and 1-bromoethene-1-sulfonyl fluoride (BESF) has been developed for constructing a class of pyridonyl aliphatic sulfonyl fluorides and pyridonyl vinyl sulfonyl fluorides in good to excellent yields. This practical method features easy operation, wide substrate scope, and mild reaction conditions.

引用

页码：835 / 845

页数：11

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