Progress on Research of Composited Hydrogel Dressings Based on Polyvinyl Alcohol in Chronic Wound

被引：0

作者：

Huang, Qiaoyu ^{[1
]}

Sun, Zhengguang ^{[1
]}

Zhang, Yuhong ^{[1
]}

Chen, Zhaoxia ^{[1
]}

机构：

[1] Hubei Key Laboratory for Precision Synthesis of Small Molecule Pharmaceuticals, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, School of Material Science and Engineering, Hubei University, Wuhan

来源：

Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering | 2024年 / 40卷 / 09期

关键词：

chronic wound; composited hydrogel; polyvinyl alcohol; wound dressing;

D O I：

10.16865/j.cnki.1000-7555.2024.0172

中图分类号：

学科分类号：

摘要：

The healing process of chronic wounds is lengthy and complex, with a risk of infection or even death during the process. Therefore, shortening treatment period and curing chronic wounds have become a research focus. Hydrogel dressings have the excellent properties such as moisturizing, hygroscopic, and biocompatible, which are beneficial to promote chronic wound healing. Polyvinyl alcohol (PVA) is inexpensive and biocompatible, and the PVA-based composite hydrogels are expected to be ideal dressings for chronic wounds. This works reviewed the common methods of preparing PVA-based composite hydrogel wound dressings such as physical, chemical and radiation cross- linking, and enumerated the applications of PVA hydrogels for chronic wound repair in the areas of hemostasis, antimicrobials, antioxidants, and promotion of cell proliferation. Besides, the deficiency of PVA- based hydrogel dressings in practical application was analyzed, and the development prospect and clinical transformation were presented. © 2024 Sichuan University. All rights reserved.

引用

页码：173 / 181

页数：8

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