A selective non-enzymatic synthesis of ribose simply from formaldehyde, metal salts and clays

被引:0
|
作者
Xu, Hao-Xing [1 ]
Zhao, Ze-Run [1 ]
Wang, Xiao [1 ,2 ]
机构
[1] Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210023, Jiangsu, Peoples R China
[2] Nanjing Univ, Frontiers Sci Ctr Crit Earth Mat Cycling, Nanjing 210023, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
PREBIOTIC SYNTHESIS; CHEMISTRY; DERIVATIVES; ORIGIN; SUGARS;
D O I
10.1039/d4cc03981e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This study demonstrates that metal-doped-clay (MDC) can be a selective platform for ribose produced from formaldehyde under abiotic conditions. Ribose exhibits superior retention compared with other carbohydrates on naturally occurring minerals on the early Earth in the presence of divalent cations. This finding offers an insight into the necessity of the emergence of ribose as the backbone of extant RNA.
引用
收藏
页码:1701 / 1704
页数:4
相关论文
共 33 条
  • [1] A plausible prebiotic selection of ribose forRNA-formation, dynamic isolation, andnucleotide synthesis based on metal-doped-clays
    Zhao, Ze-Run
    Wang, Xiao
    CHEM, 2021, 7 (12): : 3292 - 3308
  • [2] Insights into the Chemistry of Non-Enzymatic Browning Reactions in Different Ribose-Amino Acid Model Systems
    Hemmler, Daniel
    Roullier-Gall, Chloe
    Marshall, James W.
    Rychlik, Michael
    Taylor, Andrew J.
    Schmitt-Kopplin, Philippe
    SCIENTIFIC REPORTS, 2018, 8
  • [3] Total Synthesis of DHA and DPAn-3 Non-Enzymatic Oxylipins
    Guy, Alexandre
    Merad, Jeremy
    Degrange, Thomas
    Reversat, Guillaume
    Bultel-Ponce, Valerie
    Durand, Thierry
    Galano, Jean-Marie
    Oger, Camille
    SYNTHESIS-STUTTGART, 2022, 54 (05): : 1431 - 1445
  • [4] Scalable synthesis of γ-thiolysine starting from lysine and a side by side comparison with δ-thiolysine in non-enzymatic ubiquitination
    Merkx, Remco
    de Bruin, Gerjan
    Kruithof, Art
    van den Bergh, Toine
    Snip, Erwin
    Lutz, Martin
    El Oualid, Farid
    Ovaa, Huib
    CHEMICAL SCIENCE, 2013, 4 (12) : 4494 - 4498
  • [5] Discovery, Characterization, and Analogue Synthesis of Bohemamine Dimers Generated by Non-enzymatic Biosynthesis
    Fu, Peng
    Legako, Aaron
    La, Scott
    MacMillan, John B.
    CHEMISTRY-A EUROPEAN JOURNAL, 2016, 22 (10) : 3491 - 3495
  • [6] Non-enzymatic nitric oxide release from biodegradable S-nitrosothiol bound polymer: synthesis, characterization, and antibacterial effect
    Sundari, S.
    Berchmans, Sheela
    Umadevi, S.
    POLYMER BULLETIN, 2018, 75 (07) : 2971 - 2985
  • [7] Synthesis, Characterization of Guar-Containing Polyurethane Films and their Non-enzymatic Caffeic Acid Sensor Applications
    Duran, Serap Titretir
    Pasahan, Aziz
    Ayhan, Nurcan
    Gungor, Oznur
    Cengiz, Mahmut Alper
    Koytepe, Suleyman
    POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING, 2017, 56 (16) : 1741 - 1751
  • [8] The Origin of Life. A Critique of the RNA World Hypothesis in the Light of Laboratory Research into Non-enzymatic Synthesis of Ribonucleotides
    Gazda, Malgorzata
    FILOZOFIA NAUKI, 2015, 23 (03): : 113 - +
  • [9] Metal-Free Synthesis of Diaryl Sulfones from Arylsulfinic Acid Salts and Diaryliodonium Salts
    Umierski, Natalie
    Manolikakes, Georg
    ORGANIC LETTERS, 2013, 15 (01) : 188 - 191
  • [10] Simple synthesis route for fabrication of protective photo-crosslinked poly(zwitterionic) membranes for application in non-enzymatic glucose sensing
    Olejnik, Adrian
    Karczewski, Jakub
    Dolega, Anna
    Siuzdak, Katarzyna
    Cenian, Adam
    Grochowska, Katarzyna
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2022, 110 (03) : 679 - 690