A Comprehensive Review of Silymarin Extraction and Liposomal Encapsulation Techniques for Potential Applications in Food

被引：2

作者：

Makouie, Sina ^{[1
]}

Brys, Joanna ^{[1
]}

Malajowicz, Jolanta ^{[1
]}

Koczon, Piotr ^{[1
]}

Siol, Marta ^{[1
]}

Palani, Bharani K. ^{[1
]}

Brys, Andrzej ^{[2
]}

Obranovic, Marko ^{[3
]}

Mikolcevic, Sanja ^{[4
]}

Gruczynska-Sekowska, Eliza ^{[1
]}

机构：

[1] Warsaw Univ Life Sci, Inst Food Sci, Dept Chem, 159c Nowoursynowska St, PL-02776 Warsaw, Poland

[2] Warsaw Univ Life Sci, Inst Mech Engn, Dept Fundamental Engn & Energet, 164 Nowoursynowska St, PL-02787 Warsaw, Poland

[3] Univ Zagreb, Fac Food Technol & Biotechnol, Dept Food Engn, Pierottijeva 6, Zagreb 10000, Croatia

[4] Univ Appl Sci Marko Marulic Knin, Dept Food Technol, Petra Kresimira IV 30, Knin 22300, Croatia

来源：

APPLIED SCIENCES-BASEL | 2024年 / 14卷 / 18期

关键词：

silymarin; liposome technology; green extraction methods; supercritical CO2; THISTLE SILYBUM-MARIANUM; REVERSE-PHASE EVAPORATION; DRUG-DELIVERY SYSTEMS; MILK THISTLE; CARBON-DIOXIDE; ASSISTED EXTRACTION; ETHANOL INJECTION; OPTIMIZATION; FORMULATION; NANOPARTICLES;

D O I：

10.3390/app14188477

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review explores advances in silymarin extraction and liposomal encapsulation techniques, highlighting their potential applications in the food, pharmaceutical, and cosmetic industries. The study evaluates a range of extraction techniques, including supercritical fluid extraction, microwave-assisted extraction, ultrasound-assisted extraction, and enzyme-assisted extraction, emphasising their efficiency and reduced environmental impact. Furthermore, it examines conventional and innovative liposomal encapsulation techniques, including supercritical carbon dioxide encapsulation and microfluidics, which enhance silymarin's bioavailability and therapeutic effects. The integration of these methods promises more effective, safe, and eco-friendly silymarin products. This comprehensive review aims to inform readers of the latest research and future industrial applications, with a particular focus on the refinement and scaling up of these processes to meet commercial demands.

引用

页数：22

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