Iodine/DMF-Mediated Regioselective Sulfenylation Using Arenediazonium Tosylates and Sodium Metabisulfite: An Easy Access to 3-Arylthioindoles

被引：0

作者：

Rai, Aditya ^{[1
]}

Prabhakar, Neha Sharma ^{[1
]}

Kishor, Kaushal ^{[1
]}

Singh, Krishna Nand ^{[1
]}

机构：

[1] Banaras Hindu Univ, Inst Sci, Dept Chem, Varanasi 221005, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 20期

关键词：

S BOND FORMATION; C-H BONDS; QUINONE MONO-O; S-ACETALS; INDOLES; INHIBITORS; FUNCTIONALIZATION; HYDRAZIDES; SULFIDES; ESTERS; SALTS;

D O I：

10.1021/acs.joc.4c01819

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical C3 sulfenylation of indoles has been accomplished using arenediazonium tosylates and sodium metabisulfite, with a key role of iodine/DMF combination in the reaction. The method involves scarce use of sodium metabisulfite as a divalent sulfur source and offers an array of structurally diverse 3-arylthioindoles in high yields under operationally simple transition-metal-free and mild conditions.

引用

页码：15075 / 15082

页数：8