ALOE VERA-LOADED GELATIN METHACRYLOYL HYDROGELS AS POTENTIAL BONE BIOMATERIALS

被引:0
作者
Nicolae, Carmen-Valentina [1 ]
Iordache, Iulia-Maria [2 ]
Banciu, Adela [3 ]
Stancu, Izabela-Cristina [1 ]
机构
[1] Dept. of Bioresources and Polymer Science, Faculty of Chemical Engineering and Biotechnologies, Advanced Polymer Materials Group, National University of Science and Technology POLITEHNICA Bucharest, Romania
[2] Smart Biomaterials and Applications, Faculty of Medical Engineering, National University of Science and Technology POLITEHNICA Bucharest, Romania
[3] Faculty of Medical Engineering, National University of Science and Technology POLITEHNICA Bucharest, Romania
来源
UPB Scientific Bulletin, Series B: Chemistry and Materials Science | 2024年 / 86卷 / 04期
关键词
Bone - Tissue regeneration;
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摘要
This study reports the development of gelatin methacryloyl (GelMA) hydrogels loaded with aloe vera (AV) compounds as potential biomaterials for bone tissue regeneration. By incorporating lyophilized AV gel and commercially available AV powder into GelMA hydrogels, we aimed to leverage the synergistic bioactivity of AV components for comprehensive tissue regeneration. The effect of AV compounds addition to the GelMA network was investigated through gel fraction evaluation and rheological measurements. The results suggest that the formulations could meet the standards for the targeted application, while their rheological, network-forming and antibacterial properties are significantly influenced by the incorporation of lyophilized AV gel. © 2024, Politechnica University of Bucharest. All rights reserved.
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页码:131 / 144
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