Smartphone-assisted ratiometric fluorescent sensor to quantitatively detect curcumin in traditional Chinese medicine based on Förster resonance energy transfer

被引：0

作者：

Wu, Shuang ^{[1
]}

Wang, Yunhan ^{[1
]}

Han, Shikai ^{[2
]}

Hui, Ge ^{[2
]}

Teng, Ye ^{[2
]}

Liu, Wei ^{[2
]}

Zhao, Yu ^{[1
]}

机构：

[1] Changchun Univ Chinese Med, Jilin Ginseng Acad, Changchun 130017, Peoples R China

[2] Changchun Univ Chinese Med, Coll Pharm, Changchun 130017, Peoples R China

来源：

MICROCHIMICA ACTA | 2024年 / 191卷 / 10期

关键词：

Ratiometric fluorescence; Fe-MIL-88-NH2; Curcumin; F & ouml; rster resonance energy transfer; Smartphone assisted visual sensing platform; METAL-ORGANIC FRAMEWORK; CARBON DOTS; NITROGEN; PROBE; FRET;

D O I：

10.1007/s00604-024-06670-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A ratiometric fluorescence sensor (Fe-MIL-88-NH2/curcumin) based on luminescent metal-organic frameworks (LMOFs) for the determination of curcumin was constructed. Upon the addition of curcumin, the 535-nm emission of curcumin was enhanced, while the fluorescence emission at 438 nm was quenched, under 367-nm excitation. This sensor demonstrated a broad linear range from 1.5 to 40 mu M, a low detection limit of 35 nM, and a fast response time of at most 30 s. We verified the F & ouml;rster resonance energy transfer (FRET) mechanism between donor (Fe-MIL-88-NH2) and acceptor (curcumin), which further proved the selectivity of the approach. The sensing system enabled the detection of curcumin in the traditional Chinese medicine (TCM) Turmeric. A smartphone-assisted sensing platform was prepared to visually detect curcumin in a portable manner. This study represents the first attempt to fabricate LMOFs for ratiometric fluorescence detection of curcumin, which has promising potential for application in TCM.

引用

页数：9

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