Imaging Characteristics and Pathological Analysis of Primary Hepatic Neuroendocrine Neoplasms

被引：1
作者：
Li D. [1 ]
He Y. [1 ]
Xie G. [2 ]
Mao Z. [1 ]
Liu P. [1 ]
机构：
[1] Department of Radiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, No.61 Jiefang West Road, Hunan, Changsha
[2] Department of Pathology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, No.61 Jiefang West Road, Hunan, Changsha
来源：
Current Medical Imaging | 2024年 / 20卷
关键词：
Computed tomography; Gd-EOB-DTPA; Liver; Magnetic resonance imaging; Neuroendocrine neoplasms; Radiologicacharacteristics;
D O I：
10.2174/0115734056243238231031031426
中图分类号：
学科分类号：
摘要：
Aims: To investigate the radiological characteristics of the PHNENs on CT and MRI and improve the understanding of the image manifestations and preoperative diagnosis of the disease. Background: Primary hepatic neuroendocrine neoplasms (PHNENs) are rare diseases, and most of the relevant studies are case reports. Characterized by no specific clinical symptoms, PHNENs not only have a low preoperative diagnosis rate with great difficulty in early diagnosis but are frequently misdiagnosed as primary hepatic cancer. Objective: 15 PHNEN patients were enrolled, with 10 cases in the G2 stage and 5 cases in the G3 stage. Methods: The imaging and clinicopathological information of 15 patients pathologically diagnosed with PHNENs was retrospectively reviewed. Results: The average age of the patients enrolled was 46.14±18.24 years, and the average tumor size was 91.00±61.17 mm. 13 cases showed nodules or masses, 8 cases were located in the periphery of the liver, showing capsule depression and subcapsular effusion signs. CT enhanced scan showed heterogeneous and obvious enhancement in 9 arterial-phase cases, 2 cases in arterial and portal venous phases both saw mild enhancement; the enhancement degree of lesions in the G2 stage in the arterial phase was significantly higher than in the G3 stage. Gd-EOB-DTPA dynamic enhanced MRI was conducted on 3 cases, and scattered lesions with heterogeneous and slight hyperintensity were observed in the hepatobiliary-specific lesions. Image manifestations showed diffuse lesions in 2 cases, with heterogeneous enhancement in the arterial phase and decreased enhancement in the portal venous phase by the dynamic enhanced scan. Conclusion: PHNENs were the imaging characteristics of PHNENs. The CT-enhanced scanning during the arterial phase may provide a certain reference for pathological grading (G2 and G3 grades). Gd-EOB-DTPA-enhanced MRI is helpful for PHNEN diagnosis. © 2024 The Author(s). Published by Bentham Science Publisher.
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