Silsesquioxanes as Promising Materials for the Development of Electrochemical (Bio)Sensors

被引：0
作者：
Zahrebelnei, Felipe [1 ]
Ribicki, Ariane Caroline [1 ]
Martins Duboc Natal, Aline [1 ]
Fujiwara, Sérgio Toshio [1 ]
Wohnrath, Karen [1 ]
Lima, Dhésmon [2 ]
Pessôa, Christiana Andrade [1 ]
机构：
[1] Department of Chemistry, Universidade Estadual de Ponta Grossa, Avenida General Carlos Cavalcanti 4748, PR, Ponta Grossa
[2] Department of Chemistry and Physics, Mount Saint Vincent University, 166 Bedford Highway, Halifax, B3M 2J6, NS
来源：
Chemosensors | 2024年 / 12卷 / 12期
关键词：
biosensors; disease biomarkers; electrochemical impedance spectroscopy; electrochemical sensors; modified electrodes; nanomaterials; silsesquioxanes; voltammetry;
D O I：
10.3390/chemosensors12120259
中图分类号：
学科分类号：
摘要：
Silsesquioxanes (SSQs) comprise an interesting and versatile class of three-dimensional organosilicate oligomers with diverse structural arrangements and interesting physicochemical properties. SSQs are of considerable technological interest, with applications that include the development of electrochemical detection devices. The presence of functional groups on their structures enables the anchoring of different electroactive and conductive species, such as complexes, metal nanoparticles and carbon nanomaterials, and biomolecules, including enzymes, nucleic acids, and antibodies, which boosts the sensitivity and selectivity of the obtained (bio)sensors. These materials can also be incorporated into conductive matrices using a range of methods, which enhances their versatility. This mini review provides an overview of the most recent applications of hybrid organic–inorganic SSQs in the preparation of modified electrodes for the development of electrochemical sensors and biosensors. Special focus is placed on the incorporation of nanomaterials in their polymeric structure and on the design and fabrication of electrochemical devices using different strategies. © 2024 by the authors.
引用
收藏
相关论文
共 111 条
  • [1] Dong F., Lu L., Ha C.S., Silsesquioxane-Containing Hybrid Nanomaterials: Fascinating Platforms for Advanced Applications, Macromol. Chem. Phys, 220, (2019)
  • [2] Baney R.H., Itoh M., Sakakibara A., Suzuki T., Silsesquioxanes, Chem. Rev, 95, pp. 1409-1430, (1995)
  • [3] D'Arienzo M., Dire S., Redaelli M., Borovin E., Callone E., di Credico B., Morazzoni F., Pegoretti A., Scotti R., Unveiling the Hybrid Interface in Polymer Nanocomposites Enclosing Silsesquioxanes with Tunable Molecular Structure: Spectroscopic, Thermal and Mechanical Properties, J. Colloid Interface Sci, 512, pp. 609-617, (2018)
  • [4] Franco F.S., Fernandes D.S., do Carmo D.R., A Modified Hybrid Silsesquioxane/Histidine Composite for Copper and Zinc Adsorption and It Behavior in the Electro-Oxidation of Ascorbic Acid, Mater. Sci. Eng. C, 111, (2020)
  • [5] Chen M., Zhang Y., Zhang W., Li J., Polyhedral Oligomeric Silsesquioxane-Incorporated Gelatin Hydrogel Promotes Angiogenesis during Vascularized Bone Regeneration, ACS Appl. Mater. Interfaces, 12, pp. 22410-22425, (2020)
  • [6] Arsalani N., Kazeminava F., Akbari A., Hamishehkar H., Jabbari E., Kafil H.S., Synthesis of Polyhedral Oligomeric Silsesquioxane Nano-Crosslinked Poly(Ethylene Glycol)-Based Hybrid Hydrogels for Drug Delivery and Antibacterial Activity, Polym. Int, 68, pp. 667-674, (2019)
  • [7] Winiarski J.P., de Barros M.R., Wecker G.S., Nagurniak G.R., Parreira R.L.T., Affeldt R.F., Peralta R.A., Jost C.L., A Novel Hybrid Organic-Inorganic Silsesquioxane and Cobalt(Ii) Tetrasulphophthalocyanine Material as an Efficient Electrochemical Sensor for the Simultaneous Determination of the Anti-Hypertensive Nifedipine and Its Metabolite, J. Mater. Chem. C Mater, 8, pp. 6839-6850, (2020)
  • [8] Steinmetz M., Lima D., Viana A.G., Fujiwara S.T., Pessoa C.A., Etto R.M., Wohnrath K., A Sensitive Label-Free Impedimetric DNA Biosensor Based on Silsesquioxane-Functionalized Gold Nanoparticles for Zika Virus Detection, Biosens. Bioelectron, 141, (2019)
  • [9] Winiarski J.P., Rampanelli R., Bassani J.C., Mezalira D.Z., Jost C.L., Multi-Walled Carbon Nanotubes/Nickel Hydroxide Composite Applied as Electrochemical Sensor for Folic Acid (Vitamin B9) in Food Samples, J. Food Compos. Anal, 92, (2020)
  • [10] Winiarski J.P., de Barros M.R., Magosso H.A., Jost C.L., Electrochemical Reduction of Sulfite Based on Gold Nanoparticles/Silsesquioxane-Modified Electrode, Electrochim. Acta, 251, pp. 522-531, (2017)
12345678910